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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KLH-conjugated synthetic peptide encompassing a sequence within human CDC42.
- 亚型:
Chicken Ig
- 形态:
Each vial contains 0.1 ml IgY in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
多克隆
- 标记物:
见下方详细说明
- 适应物种:
H, M, R
- 宿主:
Chicken
- 应用范围:
E, WB
- 浓度:
见详细说明信息
- 靶点:
CDC42
- 抗体英文名:
CDC42 Antibody
- 抗体名:
CDC42 Antibody
- 规格:
0.1 mg
CDC42 Antibody产品详细介绍:
| 产品名称: | CDC42 Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 254045 |
| 规格: | 0.1 mg |
| 产品描述: | CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to S. cerevisiae CDC42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. CDC42 is thought to regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. At least two isoforms of CDC42 are known to exist. |
| 克隆类型: | Chicken Polyclonal Antibody |
| 亚型: | Chicken Ig |
| 免疫原: | KLH-conjugated synthetic peptide encompassing a sequence within human CDC42. |
| 适用物种: | H, M, R |
| 应用范围: | E, WB |
| 应用说明: | E: 1:500-1:1,000; WB: 1:100-1:500 |
| 别名: | CDC42; Cell division cycle 42; G25K |
| 形态: | Each vial contains 0.1 ml IgY in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: |
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文献和实验Activation and Function of Small GTPases Rho, Rac, and Cdc42 During Gastrulation
activation of Rho, Rac, and Cdc42 in both mammalian cells and Xenopus embryo explants.
Identification and Functional Reconstitution of Effector Proteins for the GTPases Rac and CDC42HS
Rho-related GTPase proteins, Rat 1,2, Rho A, B, G, and CDC42Hs, constitute a distinct subfamily in the Ras super family of GTPases ( 1 ) During the last few years a large body of evidence has been accumulated that suggests that Rho
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
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