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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
cell division cycle 42 (GTP binding protein, 25kDa)
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9GZT9
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IHC
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
CDC42
- 抗体英文名:
anti-CDC42 antibody,CDC42 antibody
- 抗体名:
anti-CDC42 抗体,CDC42 抗体
- 规格:
100μg
CDC42抗体| CDC42 antibody
货号 PAab01530
蛋白别名
蛋白介绍
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia. Mediates CDC42-dependent cell migration.
产品描述
anti-CDC42 antibody is a Rabbit Polyclonal antibody againstCDC42..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human pancreas cancer using PAab01530(CDC42 antibody) at dilution of 1:50
Western blot
mouse brain tissue were subjected to SDS PAGE followed by western blot with PAab01530(CDC42 antibody) at dilution of 1:400(本抗体仅供体外科研用途,不可用于临床诊断!)
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文献和实验Activation and Function of Small GTPases Rho, Rac, and Cdc42 During Gastrulation
activation of Rho, Rac, and Cdc42 in both mammalian cells and Xenopus embryo explants.
Identification and Functional Reconstitution of Effector Proteins for the GTPases Rac and CDC42HS
Rho-related GTPase proteins, Rat 1,2, Rho A, B, G, and CDC42Hs, constitute a distinct subfamily in the Ras super family of GTPases ( 1 ) During the last few years a large body of evidence has been accumulated that suggests that Rho
switching and for elucidating the mechanisms of Rho GTPase control of the cytoskeleton. This chapter describes FRET microscopy methods to image the distribution of GTP-bound Rac and Cdc42 during the well-defined morphological transitions of phagocytosis
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