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- 2025年07月15日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20℃
- 克隆性：
单克隆
- 抗体名：
C-Src tyrosine Kinase (CSK) (C-Term) 抗体
- 规格：
0.1ml/0.2ml
C-Src tyrosine Kinase (CSK)
别名 AW212630
抗原表位
其他选择 C-Term
适用
其他选择 人, 小鼠, 大鼠
宿主
其他选择 山羊
克隆类型
多克隆
标记
其他选择 非结合性
实验类型 Peptide ELISA
C-Src tyrosine Kinase (CSK) (C-Term) 抗体应用范围
其他选择 酶联免疫吸附测定（ELISA）, Western Blotting (WB), 免疫组织化学（IHC）
Pubmed 找到1个引用
规格 100 μg
发货至 中国 (更改)
发货时间 24至29个工作日
产品编号yb184606
产品细节
免疫原 Peptide with sequence C-EQLEHIKTHELHL, from the C Terminus of the protein sequence according to NP_004374.1, NP_001120662.1.
特异性 Reported variants represent identical protein: NP_004374.1, NP_001120662.1.
交叉反应 犬, 牛
纯化方法 Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
目标详细情况
别名 CSK
C-Src tyrosine Kinase (CSK) (C-Term) 抗体背景 Synonyms: CSK, c-src tyrosine kinase, MGC117393
基因ID 1445, 12988
NCBI登录号 NP_001120662, NP_004374
研究领域 Signaling, Tyrosine Kinases
使用细节
应用备注 ELISA: antibody detection limit dilution 1:32000.
Western blot: Approx 50 kDa band observed in lysates of cell line Jurkat and in Mouse and Rat Spleen lysates (calculated MW of 50.7 kDa according to NP_004374.1). Recommended concentration: 1-3 µg/mL.
IHC: In paraffin embedded Human Colon shows staining of a cell layer between the mucosal columns and the muscularis mucosae. Recommended concentration: 3-6 µg/mL.
限制 仅限研究用
贮存及处理
状态 Liquid
缓冲液 Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
C-Src tyrosine Kinase (CSK) (C-Term) 抗体注意事项 Minimize freezing and thawing.
储存条件 -20 °C
储存方法 Aliquot and store at -20 °C.
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文献和实验is the specificity of the antibody-antigen interaction because monoclonal antibodies bind to only one epitope of the antigen. If the antigen of interest is tyrosine phosphorylated, and this tyrosine phosphorylation is under investigation, each step has to be handled
Tyrosine Kinase Inhibitors Against EGF Receptor-Positive Malignancies
epidermal growth factor receptor (EGFR) (1 –6 ), Janus kinases (JAKs) (7 –13 ), Bruton’s tyrosine kinase (BTK) (14 –16 ), platelet-derived growth factor (PDGF) (17 ), protein kinase C (PKC) (18 –24 ), Lck (25 , 26 ), Trk (27 –30
Use of Peptide Libraries to Determine Optimal Substrates of Tyrosine Kinases
of 110 KDa; this interaction leads to phosphorylation of the protein by the catalytic domain of Src (4 ). Similarly, the SH2 domain of the Abl tyrosine kinase is required for hyperphosphorylation of rts substrate p130CAS (5 ). Substitutions of SH
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