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- 保存条件：
-20℃
- 克隆性：
单克隆
- 抗体名：
GATA Binding Protein 4 (GATA4) (N-Term) 抗体
- 规格：
0.1ml/0.2ml
GATA Binding Protein 4 (GATA4)
别名 gata-4, xgata4, xGATA-4, MGC81427, GATA4, GATA-4, Gata4, gata4, ASD2, VSD1, Gata-4, gata
抗原表位
其他选择 N-Term
适用
其他选择 小鼠, 大鼠, 犬, 猪, 人
宿主
其他选择 兔
克隆类型
多克隆
标记
其他选择 非结合性
应用范围
其他选择 Western Blotting (WB)
Pubmed 找到1个引用
规格 50 μg
发货至 中国 (更改)
发货时间 9至12个工作日
产品编号 yb183609
产品细节 GATA Binding Protein 4 (GATA4) (N-Term) 抗体
免疫原 Synthetic peptide directed towards the N terminal of human GATA4
序列 MYQSLAMAAN HGPPPGAYEA GGPGAFMHGA GAASSPVYVP TPRVPSSVLG
预测反应 Dog : 100 %, Human : 100 %, Mouse : 100 %, Rat : 100 %, Bovine : 90 %, Pig : 90 %
产品特性 This is a rabbit polyclonal antibody against GATA4. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
目标详细情况 GATA Binding Protein 4 (GATA4) (N-Term) 抗体
别名 GATA4
背景 GATA4 is a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. GATA4is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in this gene have been associated with cardiac septal defects.This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in this gene have been associated with cardiac septal defects.
分子量 45 kDa
基因ID 2626
NCBI登录号 NP_002043, NM_002052
UniProt Q5IFM8
研究领域 Hypertrophy, Lineage Markers, Transcription Factors
使用细节 GATA Binding Protein 4 (GATA4) (N-Term) 抗体
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明
Antigen size: 442 AA
限制 仅限研究用
贮存及处理 GATA Binding Protein 4 (GATA4) (N-Term) 抗体
状态 Lyophilized
溶解方式 Add 50 µL of distilled water.
浓度 1 mg/mL
缓冲液 PBS buffer with 2 % sucrose
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For longer periods of storage, store at -20 °C
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文献和实验Cell Rep Med：赵健元/孙锟/曹婧/周翔宇合作团队发现孕期高棕榈酸致子代先天性心脏病的机制
的 MARS 激活可能是叶酸不应答的诱发因素之一，在发现新型先心病致病代谢物的同时也为先心病的早期干预提供了新线索。 该研究成果在 2023 年 2 月 20 日以题为 Gestational palmitic acid suppresses embryonic GATA-binding protein 4 signaling and causes congenital heart disease 的研究论文发表于 Cell Press 细胞出版社期刊 Cell Reports Medicine 上发表
-terminally to the transcription factor of interest is very efficiently biotinylated by BirA coexpressed in the same cells, as was demonstrated by the tagging of the essential hematopoietic transcription factor GATA-1. The direct binding to streptavidin
; 0.78 IU / ampoule VWF: ristocetin cofactor; 0.94 IU / ampoule VWF: collagen binding 人凝血因子VIII原液冻干粉 11.0 IU /ampoule. 人凝血因子II, VII, IX, X血浆冻干粉 0.91 IU / (factor II), 1.00 IU (factor VII), 0.86IU (factor IX), 0.93 IU(factor X) / ampoule 人凝血因子II, and, X
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