CPE / Carboxypeptidase E抗体

CPE / Carboxypeptidase E抗体产品信息

免疫原 :
Recombinant human CPE protein ( Catalog#10069-H08H )
抗体宿主 : Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
Produced in rabbits immunized with purified, human cell-derived, recombinant human CPE ( rhCPE ; Catalog#10069-H08H ; NP_001864.1; Met 1- Ser 453 ). Total IgG was purified by Protein A affinity chromatography.
CPE / Carboxypeptidase E抗体Background
Human carboxypeptidase E (CPE), also known as Carboxypeptidase H, is a peripheral membrane protein and a zinc metallo carboxypeptidase, and the conversion of proCPE into CPE occurs primarily in secretory vesicles. The active form of CPE cleaves C-terminal amino acid residues of the peptide, and is thus involved in the biosynthesis of peptide hormones and neurotransmitters including insulin, enkephalin, etc. The enzymatic activity is enhanced by millimolar concentrations of Co2+. It has also been proposed that membrane-associated carboxypeptidase E acts as a sorting receptor for targeting regulated secretory proteins which are mostly prohormones and neuropeptides in the trans-Golgi network of the pituitary and in secretory granules into the secretory pathway. Its interaction with glycosphingolipid-cholesterol rafts at the TGN facilitates the targeting. Mutations in this gene are implicated in type I I diabetes due to impaired glucose clearance and insulin resistance.
CPE / Carboxypeptidase E抗体相关产品如下：
hz-5618R Phospho-Smad2(Thr220)磷酸化细胞信号转导分子SMAD2抗体
hz-5627R phospho-Alpha synuclein (Tyr125)磷酸化核突触蛋白α抗体
hz-5628R phospho-Alpha synuclein(Ser129)磷酸化核突触蛋白α抗体
hz-5630R phospho-SYN1(Ser549)磷酸化神经突触素1抗体
hz-5631R phospho-SYN1(Ser603) 磷酸化神经突触素1抗体
hz-5632R phospho-SYN1(Ser62+Ser67)磷酸化神经突触素1抗体
hz-5639R phospho-STXBP1 (Ser515)磷酸化神经突触前膜胞内蛋白抗体
hz-5974R SMYD3组蛋白甲基转移酶SMYD3抗体
hz-5975R SSX8滑膜肉瘤X断点蛋白8抗体
hz-5622R phospho-STAT6(Thr645)磷酸化信号转导和转录激活因子6抗体
hz-5623R Phospho-Stathmin(Ser25)磷酸化原癌基因蛋白18
hz-6257R STK38丝氨酸/苏氨酸蛋白激酶38抗体
hz-2945R SNX1分选连接蛋白1抗体
hz-6159R STARD8GTP酶激活因子STARD8抗体
hz-6186R SERPIN A11丝氨酸蛋白酶抑制剂A11抗体
hz-6523R SCRO鳞状细胞癌相关蛋白抗体
hz-5529R S100A6S100钙结合蛋白A6抗体
hz-4146R S100A11S100钙结合蛋白A11抗体
hz-4165R S100PS100钙结合蛋白P抗体
hz-4145R SYTL5突触样蛋白5亚型2抗体
hz-5942R SERINC3丝氨酸合并蛋白3抗体（肿瘤差异表达蛋白）
hz-5945R SnoNSmad核转录共抑制因子抗体
hz-5943R SETSET易位蛋白/髓系白血病相关蛋白抗体
hz-5944R SETSET易位蛋白/髓系白血病相关蛋白抗体
hz-5957R Styk1丝氨酸/苏氨酸/酪氨酸激酶STYK1抗体
hz-6684R SCN11A钠通道蛋白11α抗体
hz-6687R SCN1B钠离子通道β1抗体
hz-5817R Semaphorin 3B导向蛋白3B抗体
hz-6688R SCN8A钠通道蛋白8α抗体
hz-2923R SRPK1丝氨酸/苏氨酸蛋白激酶SRPK1抗体
hz-9213R SERPINB12丝氨酸蛋白酶抑制剂B12抗体
hz-9211R SERPINB10丝氨酸蛋白酶抑制剂B10抗体
hz-5328R 5HT3C5-羟色胺受体3C抗体
hz-11535R SLC27A4长链脂肪酸转运蛋白4抗体
hz-7014R STEAP4肿瘤坏死因子α诱导蛋白9/前列腺六跨膜上皮抗原4抗体
hz-7015R STK31丝氨酸/苏氨酸蛋白激酶31抗体
hz-4289R 5HT3B receptor5-羟色胺受体3B抗体
hz-6643R SCYL1BP1SCYL结合蛋白1抗体
hz-2959R 5HTR2C5-羟色胺受体2C抗体
hz-3660R srGAP3精神障碍相关GAP蛋白抗体
hz-3633R Synaptopodin突触足蛋白抗体
hz-2205R SLAMF9CD2F-10抗体
hz-4056R SMURF2Smad蛋白E3泛素连接酶2抗体