DCIR / CLEC4A / CLECSF6抗体

DCIR / CLEC4A / CLECSF6抗体产品信息

免疫原 :
Recombinant human CLEC4A protein ( Catalog#11476-H07H )
Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
Produced in rabbits immunized with purified, human cell-derived, recombinant human CLEC4A ( rh CLEC4A ; Catalog#11476-H07H ; NP_001128530.1 ; Gln 70 - Leu 237 ). CLEC4A specific IgG was purified by human CLEC4A affinity chromatography
DCIR / CLEC4A / CLECSF6抗体背景综述
C-type lectin domain family 4 member A, also known as C-type lectin superfamily member 6, Dendritic cell immunoreceptor, Lectin-like immunoreceptor, C-type lectin DDB27, CLEC4A and CLECSF6, is a single-pass type I I membrane protein which contains one C-type lectin domain. CLEC4A / CLECSF6 is expressed preferentially in hematopoietic tissues. It is expressed in peripheral blood leukocytes, neutrophils, moderate quantities in spleen, lymph node, and bone marrow, and at very low levels in thymus. CLEC4A / CLECSF6 contains one copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases. CLEC4A / CLECSF6 may be involved in regulating immune reactivity. It may play a role in modulating dendritic cells (DC) differentiation and/or maturation. It may also be involved via its ITIM motif (immunoreceptor tyrosine-based inhibitory motifs) in the inhibition of B-cell-receptor-mediated calcium mobilization and protein tyrosine phosphorylation.
DCIR / CLEC4A / CLECSF6抗体相关产品如下：
hz-1250hz Gax(growth arrest-specific homeobox)生长终止特异性同源盒基因抗原
hz-1288hz GDF8/MSTN(growth differntiation factor 8)生长分化因子8抗原
hz-1024hz GDNF (Glial cell line-derived neurotrphic factor)胶质细胞源性神经营养因子抗原
hz-1160hz Gelsolin凝溶胶蛋白抗原
hz-0844hz GFP绿色荧光蛋白
hz-0890hz GFP绿色荧光蛋白
hz-1173hz GITR (glucocorticoidinduced tumor necrosis factor receptor)糖皮质激素诱导肿瘤坏死因子受体抗原
hz-1206hz GLI1(GLI-Kruppel family member 1)下游转录因子Gli1蛋白抗原
hz-0933hz GLP-1/KG-31(Glucagon-like peptide-1) peptide胰高血糖素样肽-1（多肽）
hz-0085hz GLP-1 peptide胰高血糖素样肽-1（多肽）
hz-1207hz GLUT3(Glucose transporter 3)葡萄糖转运蛋白3抗原
hz-0999hz GM-CSF(Granulocyte-Macrophage Colony Stimulating Factors)粒细胞-巨噬细胞克隆刺激因子抗原
hz-1226hz GPA33(glycoprotein A33 transmembrane)糖蛋白A33(跨膜)抗原
hz-2426hz glypican 1磷脂酰基醇蛋白聚糖-1抗原
hz-1112hz GPC3(glypican 3; Intestinal protein OCI-5; GTR2-2; MXR7)磷脂酰基醇蛋白聚糖-3(多肽)
hz-2159hz Glypican 4(Glypican proteoglycan 4)磷脂酰基醇蛋白聚糖-4抗原
hz-1465hz GRB2/ASH peptide生长因子受体结合蛋白2抗原
hz-1351hz GZMB/CCPI(Granzyme B)颗粒酶B抗原
hz-1806hz UTS2R/GPR14(Urotensin II receptor：G Protein Coupled Receptor 14)G蛋白偶联受体14抗原
hz-1380hz GPR30(G Protein Coupled Receptor 30)G蛋白偶联受体30抗原
hz-1464hz GnRHR peptide促性腺激素释放激素受体抗原
hz-2501hz KiSS-1R/GPR54/GPCR54(KiSS-1 receptor/G-Protein Coupled Receptor 54)G蛋白偶联受体54抗原
hz-1209hz GRK2/BARK1 (G-protein coupled receptor kinase 2)G蛋白偶合受体激酶2抗原
hz-1161hz GRM2/GLUR2 (Glutamate Receptor Metabotropic 2)促代谢型谷氨酸受体2抗原
hz-0863hz GRO Alpha/GRO/MGSA/CXCL1 protein (growthregulated oncogene Alpha)生长调节致癌基因α/黑素瘤生长刺激因子α 抗原
hz-1219hz GRP78(glucose regulated protein 78)葡萄糖调节蛋白78抗原（热休克蛋白70蛋白5）
hz-0837hz GSR/GRase(glutathione reductase)谷胱甘肽还原酶抗原
hz-1430hz A/H1N1-M2 Human(Avian influenza Matrix Protein-2 Human)A型人流感病毒H1N1-M2蛋白多肽
hz-0422hz A/H1N1-M2 Swine(Avian influenza Matrix Protein-2 Swine)A型猪流感病毒H1N1-M2蛋白
hz-2001hz H1N1(Influenza A virus ,hemagglutinin)流感病毒A抗原
hz-2002hz H1N1(Influenza A virus ,hemagglutinin)流感病毒A抗原
hz-2560hz H2AX peptide组蛋白H2AX多肽抗原
hz-2003hz H1N1(Influenza A virus ,hemagglutinin)流感病毒A抗原
hz-2004hz H1N1(Influenza A virus ,hemagglutinin)流感病毒A抗原
hz-1235hz Haase(hyaluronidase)透明质酸酶/玻璃酸酶抗原
hz-0843hz HA tagHA tag标签多肽
hz-0966hz HA tag(map)HA tag标签（分支多肽）
hz-0540hz HAI-1(Hepatocyte Growth Factor Activator Inhibitor 1)肝细胞生长因子激活物抑制因子抗原