DCIR / CLEC4A / CLECSF6抗体

DCIR / CLEC4A / CLECSF6抗体产品信息免疫原 : Recombinant Human DCIR / CLEC4A / CLECSF6 protein (Catalog#11476-H07H)
Antibody Type : Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
克隆号 : 007
抗体宿主 : Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : This antibody was obtained from a rabbit immunized with purified, recombinant Human DCIR / CLEC4A / CLECSF6 (rh DCIR / CLEC4A / CLECSF6; Catalog#11476-H07H; NP_001128530.1; Gln 70-Leu 237).
DCIR / CLEC4A / CLECSF6抗体 Background
C-type lectin domain family 4 member A, also known as C-type lectin superfamily member 6, Dendritic cell immunoreceptor, Lectin-like immunoreceptor, C-type lectin DDB27, CLEC4A and CLECSF6, is a single-pass type II membrane protein which contains oneC-type lectin domain. CLEC4A / CLECSF6 is expressed preferentially in hematopoietic tissues. It is expressed in peripheral blood leukocytes, neutrophils, moderate quantities in spleen, lymph node, and bone marrow, and at very low levels in thymus. CLEC4A / CLECSF6 contains one copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases. CLEC4A / CLECSF6 may be involved in regulating immune reactivity. It may play a role in modulating dendritic cells (DC) differentiation and/or maturation. It may also be involved via its ITIM motif (immunoreceptor tyrosine-based inhibitory motifs) in the inhibition of B-cell-receptor-mediated calcium mobilization and protein tyrosine phosphorylation.
DCIR / CLEC4A / CLECSF6抗体相关产品如下：xy-7513R BAI1脑特异性血管生成抑制蛋白1抗体
xy-7583R BCLAF1Bcl2相关转录因子抗体
xy-6604R BCNG1脑环核苷酸门控通道蛋白1抗体
xy-5710R BRCC4乳腺癌易感基因复合蛋白4抗体
xy-4294R Bub1纺锤体检查点蛋白抗体
xy-5726R BubR1有丝分裂检验点蛋白BubR1抗体
xy-6605R BCAS3乳腺癌相关蛋白3抗体
xy-6610R BCAS2乳腺癌相关蛋白2抗体
xy-6223R BCAR1乳腺癌抗雌激素耐药蛋白1
xy-6613R BCAT1胞浆支链氨基酸酸转氨酶抗体
xy-6224R phospho-BCAR1(Tyr410)磷酸化乳腺癌抗雌激素耐药蛋白1抗体
xy-4239R BNIP3促凋亡调节蛋白BNIP3抗体
xy-4237R BMPR2骨形态发生蛋白2受体抗体
xy-6290R BRD8甲状腺激素受体共激活蛋白抗体
xy-3749R phospho-Bik(Thr33)磷酸化促凋亡Bik蛋白抗体
xy-3820R BAP135蛋白酪氨酸激酶BAP135抗体
xy-3009R phospho-BAD (Ser75)磷酸化相关死亡促进因子抗体
xy-3010R phospho-Bax (Ser184)磷酸化Bax抗体
xy-2733R Bcl-10Bcl-10抗体
xy-2734R Bcl-6/5原癌基因Bcl-6抗体
xy-3011R phospho-Bcl 10 (Ser218)磷酸化Bcl-10抗体
xy-3012R phospho-Bim(Ser87)磷酸化细胞死亡调解子抗体
xy-3013R phospho-B-Raf (Ser365)磷酸化B-Raf抗体
xy-3014R Phospho-BRCA1 (Ser1524)磷酸化乳腺癌易感基因1抗体
xy-3750R BMAL1芳香烃受体核转录蛋白样1抗体
xy-6888R BRCC3乳腺癌易感基因复合物亚基蛋白3抗体
xy-12418R BAMBI肿瘤转移抑制蛋白BAMBI抗体
xy-12393R BCL9B淋巴细胞淋巴瘤因子9抗体
xy-12868R Biliverdin Reductase胆绿素还原酶抗体
xy-12869R BIVMBIVM蛋白抗体
xy-12870R Blood Group Lewis a血型Lewis A抗原抗体
xy-12871R Blood Group Lewis b粘蛋白/岩藻糖基转移酶3抗体
xy-12872R BLMBloom综合征相关蛋白抗体