K-Ras抗体

K-Ras抗体产品信息

免疫原 :
Recombinant Human K-Ras protein (Catalog#12259-H07E)
Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
Produced in rabbits immunized with purified, recombinant Human K-Ras (rh K-Ras; Catalog#12259-H07E; AAH13572.1; Thr 2-Cys185). K-Ras specific IgG was purified by Human K-Ras affinity chromatography.
K-Ras抗体 Background
GTPase Kras, also known as K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras KRAS and KRAS2, is a cell membrane protein which belongs to thesmall GTPase superfamily and Ras family. KRAS is activated by a guanine nucleotide-exchange factor (GEF) and inactivated by a GTPase-activating protein (GAP). KRAS alternate between an inactive form bound to GDP and an active form bound to GTP. It is activated by a guanine nucleotide-exchange factor (GEF) and inactivated by a GTPase-activating protein (GAP). Defects in KRAS are a cause of acute myelogenous leukemia (AML). AML is a malignant disease in which hematopoietic precursors are arrested in an early stage of development. Defects in KRAS are a cause of juvenile myelomonocytic leukemia (JMML) which is a pediatric myelodysplastic syndrome that constitutes approximately 30% of childhood cases of myelodysplastic syndrome (MDS) and 2% of leukemia. Defects in KRAS are the cause of Noonan syndrome type 3 (NS3) which is a disorder characterized by dysmorphic facial features, short stature, hypertelorism, cardiac anomalies, deafness, motor delay, and a bleeding diathesis. Defects in KRAS are also a cause of cardiofaciocutaneous syndrome (CFC syndrome) which is characterized by a distinctive facial appearance, heart defects and mental retardation. Heart defects include pulmonic stenosis, atrial septal defects and hypertrophic cardiomyopathy.
K-Ras抗体相关产品如下：
hz-9992R C4orf144号染色体开放阅读框14抗体
hz-9552R CXorf21X染色体开放阅读框21抗体
hz-11275R phospho-CTBP1 (Ser422)磷酸化C端结合蛋白1抗体
hz-11078R Cadherin 8钙粘附蛋白8抗体
hz-9530R C6orf1928号染色体开放阅读框192抗体
hz-9982R C21orf8721号染色体开放阅读框87抗体
hz-9983R C21orf9121号染色体开放阅读框91抗体
hz-9984R C22orf2522号染色体开放阅读框25抗体
hz-9699R C20orf19620号染色体开放阅读框196抗体
hz-9483R C5orf355号染色体开放阅读框35抗体
hz-9697R C20orf19420号染色体开放阅读框194抗体
hz-9995R C4orf324号染色体开放阅读框32抗体
hz-15199R C5orf20 5号染色体开放阅读框20抗体
hz-9215R Cystatin D胱抑素D/半胱氨酸蛋白酶抑制剂D抗体
hz-9216R CST8胱抑素8/半胱氨酸蛋白酶抑制剂8抗体
hz-9217R CST9胱抑素9/半胱氨酸蛋白酶抑制剂9抗体
hz-9218R Cystatin S胱抑素S/半胱氨酸蛋白酶抑制剂S抗体
hz-6455R CHRNA3型乙酰胆碱受体α3抗体
hz-9828R C3orf333号染色体开放阅读框33抗体
hz-9830R C3orf393号染色体开放阅读框39抗体
hz-9833R C3orf593号染色体开放阅读框59抗体
hz-9484R C5orf515号染色体开放阅读框51抗体
hz-9884R C3orf703号染色体开放阅读框70抗体
hz-9810R C2orf682号染色体开放阅读框68抗体
hz-9811R C2ORF472号染色体开放阅读框47抗体
hz-4826R CD83CD83抗体
hz-9838R C17orf5917号染色体开放阅读框59抗体
hz-9839R C17ORF3917号染色体开放阅读框39抗体
hz-8524R Calcium Sensing Receptor钙敏感受体1抗体
hz-4902R Calponin 1 + 2 + 3钙结合蛋白Calponin抗体
hz-9814R C2orf442号染色体开放阅读框44抗体
hz-9817R C2orf552号染色体开放阅读框55抗体
hz-9818R C2orf572号染色体开放阅读框57抗体
hz-9821R C2orf292号染色体开放阅读框29抗体
hz-9826R C3orf213号染色体开放阅读框21抗体
hz-9792R C1ORF741号染色体开放阅读框74抗体
hz-9793R C1QTNF10补体C1q和肿瘤坏死因子相关蛋白10抗体
hz-9794R C1orf931号染色体开放阅读框93抗体
hz-9795R C1orf941号染色体开放阅读框94抗体
hz-9796R C1orf961号染色体开放阅读框96抗体
hz-9798R C1orf411号染色体开放阅读框41抗体
hz-9799R C1orf1441号染色体开放阅读框144抗体
hz-15191R C4orf34号染色体开放阅读框3抗体
hz-8558R Cathepsin S组织蛋白酶S抗体
hz-7605R Cell death inducing protein细胞死亡诱导蛋白抗体
hz-7603R Cipar1前列腺雄激素抑制信号蛋白1抗体
hz-9860R phospho-cardiac Troponin I (Thr143)磷酸化心肌肌钙蛋白抗体
hz-11126R PVRL1脊髓灰质炎受体相关蛋白1抗体
hz-13796R C19orf7319号染色体开放阅读框73抗体
hz-11127R CD11b整合素αM抗体Integrin αM
hz-11128R CASPR轴突蛋白4/少突胶质细胞抗体
hz-11129R Caspr2轴突相关CNTP2蛋白抗体（少突胶质细胞）
hz-7607R CSNK1D酪蛋白激酶δ1抗体
hz-1251R CD166活化白细胞粘附分子抗体
hz-15050R C1orf1911号染色体开放阅读框191抗体
hz-10066R Cox A16 polymerase3D柯萨奇病毒A16型聚合酶3D
hz-1272R CNTF睫状神经营养因子抗体