Autotaxin / ENPP2抗体

Autotaxin / ENPP2抗体产品信息

免疫原 :
Recombinant Mouse Autotaxin / ENPP2 protein (Catalog#50663-M07H)
Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
Produced in rabbits immunized with purified, recombinant Mouse Autotaxin / ENPP2 (rM Autotaxin / ENPP2; Catalog#50663-M07H; Q9R1E6-1; Ser 49-Ile 862). Autotaxin / ENPP2 specific IgG was purified by Mouse Autotaxin / ENPP2 affinity chromatography.
Autotaxin / ENPP2抗体 Background
Autotaxin (ATX) also known as ectonucleotide pyrophosphatase / phosphodiesterase family member 2 (NPP2 or ENPP2). It belongs to the nucleotide pyrophosphatase /phosphodiesterase family. As a catalytic protein, Autotaxin possesses lysophospholipase D activity, and thus involved in cellular membrane lipid metabolism and remodeling. Autotaxin is discovered in human melanoma cells, has been gaining attention because it could be involved in cancer invasion and metastasis as an autocrine motility factor. Recent evidence has indicated that ATX is a key enzyme in the synthesis of lysophosphatidic acid (LPA), a lipid mediator with a wide range of biological actions including the stimulation of proliferation and contraction in hepatic stellate cells, a pivotal player in hepatic fibrosis. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. Thus, Autotaxin involves in several motility-related processes such as angiogenesis and neurite outgrowth. It was found acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Additionally, Autotaxin / ENPP2 was thought as a culprit protein for cancer, which potently stimulates cancer cell proliferation and tumor cell motility, augments the tumorigenicity and induces angiogenic responses.]
Autotaxin / ENPP2抗体相关产品如下：
hz-0069hz NKA(Neurokinin A)神经激肽A抗原
hz-2411hz NKG2A/CD159a/KLRC1NK细胞受体2A/自然杀伤细胞活化性受体2A抗原
hz-0938hz NKG2D(natural killer cell group 2D)NK细胞受体/自然杀伤细胞活化性受体
hz-0688hz Nm23(NDP Kinase A,NDPKA)肿瘤转移抑制基因抗原
hz-1066hz Nm23-H1 (nucleoside dIPhosphatase kinase A)肿瘤抑制基因抗原
hz-1315hz Nogo-B/A轴索过度生长抑制因子-B/A抗原
hz-2072hz NOS-2 peptide一氧化氮合成酶-2多肽抗原
hz-1335hz Notch1/MOTC(Neurogenic locus notch homolog protein 1)跨膜受体蛋白Notch-1抗原
hz-1537hz NADPH peptide还原型辅酶Ⅱ抗原
hz-1069hz proCNP/NPPC (pro-natriuretic peptide)促尿钠排泄肽前体C抗原
hz-0937hz NPY2R(Neuropeptide Y Receptor Type 2)神经肽Y受体2（多肽）
hz-1070hz NPY1R (neuropeptide Y1 receptor)神经肽Y1受体抗原
hz-2184hz NQO1(NAD(P)H:quinone oxidoreductase l)醌氧化还原酶抗原
hz-1068hz NR1/NMDAR1(N-Methyl-d-Asprtate receptor 1)谷氨酸受体1（多肽）
hz-2030hz NR1/NMDAR1/GLUR1(N-Methyl-d-Asprtate receptor 1)谷氨酸受体1抗原
hz-2175hz NR1/NMDAR1谷氨酸受体1
hz-1067hz NR2C/NMDAR2C(N-Methyl-d-Asprtate receptor 2C)谷氨酸受体2C（多肽）
hz-1146hz N-ras原癌基因抗原
hz-1074hz Nrf2 peptide核因子2相关因子2抗原
hz-1342hz NRF-1(nuclear respiratory factor-1)核呼吸因子-1抗原
hz-1958hz NTCP(Na+/taurocholate Cotransporting Polypeptide)钠离子/牛磺胆酸共转运蛋白抗原
hz-1375hz Ghrelin 28脑肠肽28
hz-1495hz OCLN(Occluding)咬合蛋白抗原
hz-1111hz Oct-4(Octamer-4)胚胎干细胞关键蛋白抗原
hz-1294hz ODC(Ornithine decarboxylase)鸟氨酸脱羧酶抗原
hz-2086hz ompF(putative outer membrane porin F protein)小肠结肠炎耶尔森氏菌膜通道蛋白抗原
hz-2173hz OLFM1 peptide嗅球蛋白1多肽抗原
hz-1181hz ORX-A(orexin-A)增食欲素-A/欲激素A抗原
hz-1314hz OTR(oxytocin receptor)缩宫素受体
hz-1095hz OXR (Orexin receptor)食欲素受体(多肽)
hz-1483hz P2P-R/RBBP6(proliferation potential protein related)增殖潜能相关蛋白抗原
hz-0534hz P19ARFp19ARF抑癌基因抗原
hz-2210hz phospho-p38 ERK/MAPK14 (pThr180/pTyr182) peptide磷酸化丝裂原活化蛋白激酶p38抗原
hz-1689hz MKK3(MAP Kinase Kinase 3)丝裂原活化蛋白激酶MKK3/6抗原
hz-2090hz P53(wt-p53)肿瘤抑制基因抗原（野生型P53）
hz-0913hz Mtp53(Mutant type p53)突变型P53抗原
hz-0942hz WIG-1(wtp53-induced gene 1)野生型p53诱导基因1抗原
hz-1346hz P73 proteinP73肿瘤抑制基因抗原
hz-1426hz p70 S6 Kinase/P70 Beta1p70S6Kb抗原
hz-0588hz PALB2(partner and locaizer of BRCA2)乳腺癌易感基因相关蛋白2
hz-1478hz PAFR/PTAFR血小板活化因子受体抗原
hz-2270hz Phospho-PAK4 (Ser99) peptide磷酸化p21激活激酶4多肽抗原
hz-0655hz PAK7/PAK5/MBT激活激酶PAK7/PAK5抗原
hz-0828hz PAR-1 (Protease-activated receptors-1)蛋白酶激活受体-1抗原