Carbonic Anhydrase IX / CAR9抗体

Carbonic Anhydrase IX / CAR9抗体产品信息

免疫原 :
Recombinant Mouse Carbonic Anhydrase IX / CAR9 protein (Catalog#50660-M08H)
Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
Produced in rabbits immunized with purified, recombinant Mouse Carbonic Anhydrase IX / CAR9 (rM Carbonic Anhydrase IX / CAR9; Catalog#50660-M08H; NP_647466.2; Met 1-Asp 390). Carbonic Anhydrase IX / CAR9 specific IgG was purified by Mouse Carbonic Anhydrase IX / CAR9 affinity chromatography.
Carbonic Anhydrase IX / CAR9抗体 Background
Carbonic anhydrases IX (CAIX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3-) and thus participate in a variety of biological and physical processes. CAIX is a transmembrane protein structurally consisting of a signal peptide, a proteoglycan-related region, a CA domain with a highly conserved active site, a transmembrane anchor and an intracytoplasmic tail, and is the only tumor-associated CA isoenzyme known so far. Compared with normal tissues, CAIX is overexpressed in a wide spectrum of tumor types and associated with increased metastasis and poor prognosis in aggressive carcinomas. CAIX expression is cell density dependent and has been shown to be strongly induced by hypoxia, accordingly facilitates adaptation of tumor cells to hypoxic conditions. CA9 is thus regarded as a new therapeutic target for CA9-derived carcinomas.
Carbonic Anhydrase IX / CAR9抗体相关产品如下：
hz-0110hz Fe65 protein peptideFe65 蛋白（多肽抗原）
hz-0229hz FGF1 (aFGF )(ECGF-beta)(HBGF-1)肝素结合生长因子( 酸性成纤维细胞生长因子）（多肽片断抗原）
hz-0315hz fgL2 (Fibrinogen-like 2)凝血酶原酶 (又称：纤维介素蛋白；前凝血素)
hz-0119hz FLIP S/L peptide凋亡调节基因之一（多肽抗原）
hz-0269hz FoxP3叉头蛋白3-T细胞转录因子（多肽抗原）
hz-0154hz GAP-43 ( Growth associated protein-43 )生长相关蛋白-43（抗原）
hz-0010hz Gastrin胃泌素（抗原）
hz-0840hz AMACR/P504S(alpha-methylacyl-CoA racemase)α－甲基酰基辅酶A消旋酶抗原
hz-0199hz GFAP(Glial Fibrillary Acidic Protein)胶质纤维酸性蛋白（抗原）
hz-1116hz AMPK Beta1 (AMP-activated Protein Kinase beta-1)腺苷单磷酸活化蛋白激酶β1抗原
hz-0424hz MMP-1基质金属蛋白酶-1
hz-0412hz MMP-2基质金属蛋白酶-2(多肽抗原)
hz-0413hz MMP-3(matrix metalloproteinase-3/Transin-1/SL-1/Stromelysin-1 precursor)基质金属蛋白酶-3(抗原)
hz-0423hz MMP-7(Matrilysin/matrix metalloproteinases-7)基质金属蛋白酶-7(抗原)
hz-0414hz MMP-14(Matrix metalloproteinase-14)金属基质蛋白酶-14
hz-0201hz GFRAlpha-1(GDNF family receptor alpha-1)GDNF家族受体α-1（抗原）
hz-0587hz Ang- II (Angiotensin II )血管紧张素II抗原
hz-0351hz GLUT2(Glucose transporter type 2)葡萄糖转运蛋白2（抗原）
hz-2040hz ANP(atrial natriuretic peptide)心钠肽（心钠素）抗原
hz-0168hz GFRA4 ( Persephin receptor ) (GFR receptor alpha 4)GDNF家族受体α-4（抗原）
hz-0205hz GHRF (GHRH)生长激素释放激素（因子）（抗原）
hz-0800hz ANGPTL1/ANG-1 (Angiopoietin-like Protein 1)血管位蛋白样1/血管生成素样蛋白-1抗原
hz-0384hz GLUT4(Glucose transporter type 4)葡萄糖转运蛋白4（抗原）
hz-0098hz GIP (Gastric Inhibitory polypeptide)胃泌素抑制肽（抗原）
hz-0537hz ANGPTL2/ANG-2 (Angiopoietin-like Protein 2)血管位蛋白样2/血管生成素样蛋白-2（多肽）
hz-0208hz GLP-2(Glucagon-like peptide-2)胰高血糖素样肽-2（多肽抗原）
hz-0194hz GRP94 (gp96)94kDa 糖调节蛋白（抗原）
hz-1171hz Annexin A膜粘连蛋白 A抗原
hz-0348hz G Protein(Guanine nucleotide-binding regulatory protein)G蛋白（鸟苷酸结合蛋白）（抗原）
hz-0252hz GR (Glucocorticoid receptor)糖皮质激素受体 多肽
hz-0576hz Annexin II膜粘连蛋白-2抗原
hz-0341hz CKR-L2( G protein-coupled receptor-2 )G蛋白偶联受体-2(抗原)
hz-0136hz GTP-CH-1三磷酸鸟苷环水解酶（抗原）
hz-0344hz H5N1-M2(Avian influenza Matrix Protein-2)H5N1流感病毒M2型（抗原）
hz-0221hz HCV-Core丙型肝炎病毒-C区（多肽）