Fragile histidine triad / FHIT

Fragile histidine triad / FHIT抗体产品信息

免疫原 :
Recombinant Human Fragile histidine triad / FHIT protein (Catalog#14434-H08E)
Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
Produced in rabbits immunized with purified, recombinant Human Fragile histidine triad / FHIT (rh Fragile histidine triad / FHIT; Catalog#14434-H08E; P49789; Met1-Gln147). Total IgG was purified by Protein A affinity chromatography.
Fragile histidine triad / FHIT抗体 Background
Fragile histidine triad, also known as FHIT, may play a key role in differentiating humans from apes. Fragile histidine triad gene belongs to the histidine triad gene family. The exact molecular function of FHIT is still partially unclear. It has been shown that fragile histidine triad synergizes with VHL, another tumor suppressor, in protecting against chemically - induced lung cancer. Fragile histidine triad gene works as a tumor suppressor as it has been demonstrated in animal studies. It also acts as a tumor suppressor of HER2/neu driven breast cancer.
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