CD32a / Fc gamma RIIA抗体

CD32a / Fc gamma RIIA抗体产品信息

免疫原 :
Recombinant Human CD32a protein (Catalog#10374-H08H)
Antibody Type : Mouse Monoclonal Antibody ( Mouse mAb Service Platform )
克隆号 :
7D7G8B6
抗体宿主 :
Mouse IgG1
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD32a / Fc gamma RIIA (rh CD32a / Fc gamma RIIA; Catalog#10374-H08H; P12318-1; Met 1-Ile 218). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
CD32a / Fc gamma RIIA抗体Background
Receptors that recognize the Fc portion of IgG (Fcγ Rs) functions in the regulation of immune response and are divided into three classes designated Fcγ RI (CD64), Fcγ RII (CD32), and Fcγ RIII (CD16). Fcγ RI binds IgG with high affinity and functions during early immune responses, whereas Fcγ RII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses. Human CD32 class is encoded by three closely related genes, and designated Fcγ RII A, B, and C which share 94 - 99% amino acid identity in their extracellular domains but differ substantially in their transmembrane and cytoplasmic domains. Fcγ RII A is expressed on cells of both myeloid and lymphoid lineages as well as on cells of non-hematopoietic origin. Associated with an ITAM (immunoreceptor tyrosine-based activation motif)- bearing adapter subunit, Fc Rγ, CD32a (Fcγ RII A) delivers an activating signal upon ligand binding, and results in the initiation of inflammatory responses including cytolysis, phagocytosis, degranulation and cytokine production. The responses can be modulated by signals from the coexpressed inhibitory receptors such as Fcγ RII B, and the strength of the signal is dependent on the ratio of expression of the activating and inhibitory receptors.
CD32a / Fc gamma RIIA抗体相关产品如下：
hz-13380R GLT28D1糖基转移酶28家族1抗体
hz-13381R GLT6D1糖基转移酶6结构1抗体
hz-13382R GLTSCR2胶质瘤抑癌候选基因2抗体
hz-13384R Phospho-Glucocorticoid Receptor (Ser226)磷酸化糖皮质激素受体抗体
hz-13388R GLUT6葡萄糖转运蛋白6抗体
hz-13385R Glucocorticoid Receptor beta糖皮质激素受体β抗体
hz-13386R Glucose 6 phosphatase 2胰岛葡萄糖6磷酸酶2抗体
hz-13387R Glucose Oxidase葡萄糖氧化酶抗体
hz-13389R Glucosidase 2 subunit beta葡萄糖苷酶2β/Glucosidase IIβ抗体
hz-13390R GLUD2谷氨酸脱氢酶2抗体
hz-13391R phospho-GluR1 (Thr840)磷酸化谷氨酸受体1抗体
hz-13392R GGHγ-谷氨酰水解酶抗体
hz-13393R Glutamyl Prolyl tRNA synthetase/ProRS谷氨酰-脯氨酰-tRNA合成酶抗体
hz-13394R Glutaredoxin 2谷氧还蛋白2抗体
hz-13395R Glutaredoxin 5谷氧还蛋白5抗体
hz-13396R GPX2谷胱甘肽过氧化酶2抗体
hz-13397R GPX7谷胱甘肽过氧化酶7抗体
hz-13398R GSTA1谷胱甘肽S转移酶α1抗体
hz-13399R GSTK1谷胱甘肽S转移酶κ抗体
hz-3983R Galactose kinase半乳糖激酶1抗体
hz-3991R GYG2糖原蛋白2抗体
hz-3984R GALT磷酸半乳糖尿苷酸转移酶1抗体
hz-3990R GYG1糖原蛋白1抗体
hz-3989R Glycogen synthase 2葡萄糖合成酶2抗体
hz-3985R GOT2谷草转氨酶2抗体
hz-3987R Glucose 6 Phosphate Dehydrogenase葡萄糖-6磷酸脱氢酶抗体
hz-3988R GLUT5葡萄糖转运蛋白5抗体
hz-2359R Glycogen葡萄糖合成酶1抗体
hz-13502R GPATCH8G蛋白修补结构域蛋白8抗体
hz-13368R GK3甘油激酶3抗体
hz-13489R GOLPH3L高尔基体磷蛋白3样蛋白抗体
hz-8446R phospho-GluR1 (Ser849)磷酸化谷氨酸受体1抗体
hz-13498R GPATCH1/ECGPG蛋白修补结构域蛋白1抗体
hz-5374R phospho-GIT1(Tyr510) 磷酸化G蛋白偶联受体激酶相互作用蛋白1抗体
hz-5373R phospho-GIT1(Tyr554) 磷酸化G蛋白偶联受体激酶相互作用蛋白1
hz-2356R GKRP葡萄糖激酶调节蛋白抗体
hz-3893R GTPBP10GTP结合蛋白10抗体
hz-5376R phospho-G3BP1(Ser232)磷酸化Ras GTP酶活化蛋白结合蛋白1抗体
hz-4111R G3BP1Ras GTP酶活化蛋白结合蛋白1抗体