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- 文献和实验
- 技术资料
- 保存条件：
常温，避光
- 克隆性：
单克隆
- 抗体名：
CD111 / Nectin-1 / PVRL1抗体
CD111 / Nectin-1 / PVRL1抗体产品信息
免疫原 :
Recombinant Human CD111 / Nectin-1 / PVRL1 protein (Catalog#11611-H08H)
Reagents : PE-conjugated mouse monoclonal antibody
Clone ID :
09
抗体宿主 :
Mouse IgG2b
Concentration :
10 μl/Test, 0.1 mg/ml
缓冲液 : Aqueous solution containing 0.5% BSA and 0.09% sodium azide
制备方法 :
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD111 / Nectin-1 / PVRL1 (rh CD111 / Nectin-1 / PVRL1; Catalog#11611-H08H; NP_002846.3; Met 1-Thr 334) and conjugated with PE under optimum conditions, the unreacted PE was removed.
CD111 / Nectin-1 / PVRL1抗体Background
Poliovirus receptor-related protein 1, also known as Herpes virus entry mediator C, Nectin-1, Herpesvirus Ig-like receptor, CD111, PVRL1 and HVEC, is a single-pass type I membrane protein which belongs to thenectin family. PVRL1 acts in the initiation and maintenance of epithelial adherens junctions. Both rare and common mutations within PVRL1 make a minor contribution to disrupting the initiation and regulation of cell-to-cell adhesion and downstream morphogenesis of the embryonic face. PVRL1 can form trans-heterodimers with PVRL3 / nectin-3 and with PVRL4 / nectin-4. PVRL1 interacts (via C-terminus) with afadin (via PDZ domain). This interaction recruits PVRL1 to cadherin-based adherens junctions. PVRL1 interacts with integrin alphaV / beta3. It also interacts with herpes simplex virus 1 (HHV-1), herpes simplex virus 2 (HHV-2), and pseudorabies virus (PRV) envelope glycoprotein D. PVRL1 functions as an entry receptor for these viruses. Defects in PVRL1 are the cause of ectodermal dysplasia Margarita Island type (EDMI), also known as Zlotogora-Ogur syndrome, cleft lip/palate-ectodermal dysplasia syndrome (CLPED1) or ectodermal dysplasia 4. Defects in PVRL1 are also the cause of non-syndromic orofacial cleft type 7 (OFC7). Non-syndromic orofacial cleft is a common birth defect consisting of cleft lips with or without cleft palate.
CD111 / Nectin-1 / PVRL1抗体相关产品如下：
hz-0358hz-AF488 Donkey Anti-Guinea pig IgG/Alexa Fluor 488Alexa Fluor 488标记的驴抗豚鼠IgG
hz-0358hz-hzy5.5 Donkey Anti-Guinea pig IgG/Cy5.5Cy5.5标记的驴抗豚鼠IgG
hz-0358hz-hzE-hzY5 Donkey Anti-Guinea pig IgG/PE-CY5PE-CY5标记的驴抗豚鼠IgG
hz-0358hz-Ahzhz Donkey Anti-Guinea pig IgG/APCAPC标记的驴抗豚鼠IgG
hz-0358hz-Ahz Donkey Anti-Guinea pig IgG/AP碱性磷酸酶（AP）标记的驴抗豚鼠IgG
hz-0358hz-FIThz Donkey Anti-Guinea pig IgG/FITCFITC标记的驴抗豚鼠IgG
hz-0358hz-RBIThz Donkey Anti-Guinea pig IgG/RBITC罗丹明标记的驴抗豚鼠IgG
hzm-0297M-RBIThz Mouse Anti-human IgG(3D3)/RBITC罗丹明标记的鼠抗人IgG单克隆抗体
hzm-0297M-Golhz Mouse Anti-human IgG(3D3)/Gold胶体金标记的鼠抗人IgG单克隆抗体
hzm-0297M-FIThz Mouse Anti-human IgG(3D3)/FITCFITC标记的鼠抗人IgG单克隆抗体
hzm-0297M-Ahz Mouse Anti-human IgG(3D3)/AP碱性磷酸酶（AP）标记的鼠抗人IgG单克隆抗体
hzm-0297M-hzE-hzy3 Mouse Anti-human IgG(3D3)/PE-Cy3PE-Cy3标记的鼠抗人IgG单克隆抗体
hzm-0297M-hzE-hzY5 Mouse Anti-human IgG(3D3)/PE-CY5PE-CY5标记的鼠抗人IgG单克隆抗体
hzm-0297M-Ahzhz Mouse Anti-human IgG(3D3)/APCAPC标记的鼠抗人IgG单克隆抗体
hzm-0297M-AF350 Mouse Anti-human IgG(3D3)/Alexa Fluor 350Alexa Fluor 350标记的鼠抗人IgG单克隆抗体
hzm-0297M-AF488 Mouse Anti-human IgG(3D3)/Alexa Fluor 488Alexa Fluor 488标记的鼠抗人IgG单克隆抗体
hzm-0297M-AF555 Mouse Anti-human IgG(3D3)/Alexa Fluor 555Alexa Fluor 555标记的鼠抗人IgG单克隆抗体
hzm-0297M-AF647 Mouse Anti-human IgG(3D3)/Alexa Fluor 647Alexa Fluor 647标记的鼠抗人IgG单克隆抗体
hzm-0297M-hzE-hzy5.5 Mouse Anti-human IgG(3D3)/PE-Cy5.5PE-Cy5.5标记的鼠抗人IgG单克隆抗体
hzm-0297M-hzE-hzy7 Mouse Anti-human IgG(3D3)/PE-Cy7PE-Cy7标记的鼠抗人IgG单克隆抗体
hzm-0297M-hzy5.5 Mouse Anti-human IgG(3D3)/Cy5.5Cy5.5标记的鼠抗人IgG单克隆抗体
hzm-0297M-hzy7 Mouse Anti-human IgG(3D3)/Cy7Cy7标记的鼠抗人IgG单克隆抗体
hzm-0297M-hzy3 Mouse Anti-human IgG(3D3)/Cy3Cy3标记的鼠抗人IgG单克隆抗体
hzm-0297M-hzy5 Mouse Anti-human IgG(3D3)/Cy5Cy5标记的鼠抗人IgG单克隆抗体
五、蛋白质与多肽
编号 名 称
hz-0292hz BSA (bovine serum albumin)牛血清白蛋白（第五组分）
hzH-2 Protein G/FITCFITC标记蛋白-G
hzsl-hz8280 Cholesterol胆固醇
hz-0104hz Beta-Amyloid(1-16)β淀粉样肽1-16（多肽蛋白）
hz-0871hz Beta-Amyloid (31-35)β淀粉样肽31-35（多肽蛋白）
hz-0105hz Beta-Amyloid(1-28)β淀粉样肽1-28（多肽蛋白）
hz-0106hz Beta-Amyloid(1-40)β淀粉样肽（1-40）（多肽蛋白）
Y-0113 A Beta1-40 (mutation type, MT) peptide突变型β淀粉样肽1-40
hz-0107hz Beta-Amyloid (1-42)β淀粉样肽（1-42）
hz-0057hz Amylin糖尿病相关肽（胰岛淀粉样肽）
hz-0616hz CCP peptide (cyclic citrullinated peptide,CCP)瓜氨酸环肽
免疫原 :
Recombinant Human CD111 / Nectin-1 / PVRL1 protein (Catalog#11611-H08H)
Reagents : PE-conjugated mouse monoclonal antibody
Clone ID :
09
抗体宿主 :
Mouse IgG2b
Concentration :
10 μl/Test, 0.1 mg/ml
缓冲液 : Aqueous solution containing 0.5% BSA and 0.09% sodium azide
制备方法 :
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD111 / Nectin-1 / PVRL1 (rh CD111 / Nectin-1 / PVRL1; Catalog#11611-H08H; NP_002846.3; Met 1-Thr 334) and conjugated with PE under optimum conditions, the unreacted PE was removed.
CD111 / Nectin-1 / PVRL1抗体Background
Poliovirus receptor-related protein 1, also known as Herpes virus entry mediator C, Nectin-1, Herpesvirus Ig-like receptor, CD111, PVRL1 and HVEC, is a single-pass type I membrane protein which belongs to thenectin family. PVRL1 acts in the initiation and maintenance of epithelial adherens junctions. Both rare and common mutations within PVRL1 make a minor contribution to disrupting the initiation and regulation of cell-to-cell adhesion and downstream morphogenesis of the embryonic face. PVRL1 can form trans-heterodimers with PVRL3 / nectin-3 and with PVRL4 / nectin-4. PVRL1 interacts (via C-terminus) with afadin (via PDZ domain). This interaction recruits PVRL1 to cadherin-based adherens junctions. PVRL1 interacts with integrin alphaV / beta3. It also interacts with herpes simplex virus 1 (HHV-1), herpes simplex virus 2 (HHV-2), and pseudorabies virus (PRV) envelope glycoprotein D. PVRL1 functions as an entry receptor for these viruses. Defects in PVRL1 are the cause of ectodermal dysplasia Margarita Island type (EDMI), also known as Zlotogora-Ogur syndrome, cleft lip/palate-ectodermal dysplasia syndrome (CLPED1) or ectodermal dysplasia 4. Defects in PVRL1 are also the cause of non-syndromic orofacial cleft type 7 (OFC7). Non-syndromic orofacial cleft is a common birth defect consisting of cleft lips with or without cleft palate.
CD111 / Nectin-1 / PVRL1抗体相关产品如下：
hz-0358hz-AF488 Donkey Anti-Guinea pig IgG/Alexa Fluor 488Alexa Fluor 488标记的驴抗豚鼠IgG
hz-0358hz-hzy5.5 Donkey Anti-Guinea pig IgG/Cy5.5Cy5.5标记的驴抗豚鼠IgG
hz-0358hz-hzE-hzY5 Donkey Anti-Guinea pig IgG/PE-CY5PE-CY5标记的驴抗豚鼠IgG
hz-0358hz-Ahzhz Donkey Anti-Guinea pig IgG/APCAPC标记的驴抗豚鼠IgG
hz-0358hz-Ahz Donkey Anti-Guinea pig IgG/AP碱性磷酸酶（AP）标记的驴抗豚鼠IgG
hz-0358hz-FIThz Donkey Anti-Guinea pig IgG/FITCFITC标记的驴抗豚鼠IgG
hz-0358hz-RBIThz Donkey Anti-Guinea pig IgG/RBITC罗丹明标记的驴抗豚鼠IgG
hzm-0297M-RBIThz Mouse Anti-human IgG(3D3)/RBITC罗丹明标记的鼠抗人IgG单克隆抗体
hzm-0297M-Golhz Mouse Anti-human IgG(3D3)/Gold胶体金标记的鼠抗人IgG单克隆抗体
hzm-0297M-FIThz Mouse Anti-human IgG(3D3)/FITCFITC标记的鼠抗人IgG单克隆抗体
hzm-0297M-Ahz Mouse Anti-human IgG(3D3)/AP碱性磷酸酶（AP）标记的鼠抗人IgG单克隆抗体
hzm-0297M-hzE-hzy3 Mouse Anti-human IgG(3D3)/PE-Cy3PE-Cy3标记的鼠抗人IgG单克隆抗体
hzm-0297M-hzE-hzY5 Mouse Anti-human IgG(3D3)/PE-CY5PE-CY5标记的鼠抗人IgG单克隆抗体
hzm-0297M-Ahzhz Mouse Anti-human IgG(3D3)/APCAPC标记的鼠抗人IgG单克隆抗体
hzm-0297M-AF350 Mouse Anti-human IgG(3D3)/Alexa Fluor 350Alexa Fluor 350标记的鼠抗人IgG单克隆抗体
hzm-0297M-AF488 Mouse Anti-human IgG(3D3)/Alexa Fluor 488Alexa Fluor 488标记的鼠抗人IgG单克隆抗体
hzm-0297M-AF555 Mouse Anti-human IgG(3D3)/Alexa Fluor 555Alexa Fluor 555标记的鼠抗人IgG单克隆抗体
hzm-0297M-AF647 Mouse Anti-human IgG(3D3)/Alexa Fluor 647Alexa Fluor 647标记的鼠抗人IgG单克隆抗体
hzm-0297M-hzE-hzy5.5 Mouse Anti-human IgG(3D3)/PE-Cy5.5PE-Cy5.5标记的鼠抗人IgG单克隆抗体
hzm-0297M-hzE-hzy7 Mouse Anti-human IgG(3D3)/PE-Cy7PE-Cy7标记的鼠抗人IgG单克隆抗体
hzm-0297M-hzy5.5 Mouse Anti-human IgG(3D3)/Cy5.5Cy5.5标记的鼠抗人IgG单克隆抗体
hzm-0297M-hzy7 Mouse Anti-human IgG(3D3)/Cy7Cy7标记的鼠抗人IgG单克隆抗体
hzm-0297M-hzy3 Mouse Anti-human IgG(3D3)/Cy3Cy3标记的鼠抗人IgG单克隆抗体
hzm-0297M-hzy5 Mouse Anti-human IgG(3D3)/Cy5Cy5标记的鼠抗人IgG单克隆抗体
五、蛋白质与多肽
编号 名 称
hz-0292hz BSA (bovine serum albumin)牛血清白蛋白（第五组分）
hzH-2 Protein G/FITCFITC标记蛋白-G
hzsl-hz8280 Cholesterol胆固醇
hz-0104hz Beta-Amyloid(1-16)β淀粉样肽1-16（多肽蛋白）
hz-0871hz Beta-Amyloid (31-35)β淀粉样肽31-35（多肽蛋白）
hz-0105hz Beta-Amyloid(1-28)β淀粉样肽1-28（多肽蛋白）
hz-0106hz Beta-Amyloid(1-40)β淀粉样肽（1-40）（多肽蛋白）
Y-0113 A Beta1-40 (mutation type, MT) peptide突变型β淀粉样肽1-40
hz-0107hz Beta-Amyloid (1-42)β淀粉样肽（1-42）
hz-0057hz Amylin糖尿病相关肽（胰岛淀粉样肽）
hz-0616hz CCP peptide (cyclic citrullinated peptide,CCP)瓜氨酸环肽
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CD111 / Nectin-1 / PVRL1抗体
询价
