CD116 / GM-CSFR抗体

CD116 / GM-CSFR抗体产品信息

免疫原 :
Recombinant Human CD116 / GM-CSFR protein (Catalog#10701-H08H)
Reagents : PE-conjugated mouse monoclonal antibody
Clone ID :
03
抗体宿主 :
Mouse IgG1
Concentration :
5 μl/Test, 0.1 mg/ml
缓冲液 : Aqueous solution containing 0.5% BSA and 0.09% sodium azide
制备方法 :
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD116 / GM-CSFR (rh CD116 / GM-CSFR; Catalog#10701-H08H; P15509-1; Met1-Gly320) and conjugated with PE under optimum conditions, the unreacted PE was removed.
CD116 / GM-CSFR抗体 Background
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a hematopoietic cytokine that regulates differentiation, survival, and proliferation of colony-forming unit-granulocyte-macrophage progenitor cells. It performs biological functions by binding with high affinity to a specific receptor complex which is composed of a cytokine-specific alpha-chain (GM-CSF receptor alpha-chain, αGMR) and a beta-chain shared with the receptors for interleukin-3 and interleukin-5. GM-CSFR has been identified to mediate the activation of Janus kinase (Jak)- Stat and MAPK pathways. The alpha subunit binds GM-CSF with low affinity, whereas the beta subunit does not bind GM-CSF by itself. Although the cytoplasmic domain of αGMR is short (54 aa), it is essential for cell differentiation, proliferation, and survival induced by GM-CSF. αGMR also appears to have a role independent of βGMR in that αGMR signals for increased glucose transport through activation of phosphatidylinositol 3-kinase.
CD116 / GM-CSFR抗体相关产品如下：
hz-5951R LIMS1整合素和生长因子样蛋白1抗体
hz-4771R LLGL2相似肿瘤抑制基因HUGL抗体
hz-13687R LAMTOR1LAMTOR1蛋白抗体
hz-13649R LDB3LIM结构域结合蛋白3抗体
hz-13650R LIMS2ILK结合蛋白LIMS2抗体
hz-13651R LNK淋巴细胞特异性接头蛋白抗体
hz-7349R LILRB2细胞表面免疫球蛋白样转录因子4抗体
hz-13652R LY6G6F淋巴细胞抗原6重复位点蛋白G6F抗体
hz-13653R Leupaxin桩蛋白抗体
hz-6055R LRPAP1脂蛋白受体相关蛋白/低密度脂蛋白相关蛋白的相关蛋白1抗体
hz-6068R LEPREL2皮屑样蛋白2抗体
hz-1969R LAMA3层粘蛋白α3抗体
hz-1970R LAMP1溶酶体相关膜蛋白1抗体
hz-1971R Lxn/Latexin羧肽酶抑制剂抗体
hz-1972R LCAT卵磷酯胆固醇酰基转移酶抗体
hz-1973R LPL/PLASTIN2脂蛋白脂酶抗体
hz-0961R Leptin receptor瘦素受体抗体
hz-2905R LRP6低密度脂蛋白受体相关蛋白6抗体
hz-3253R Phospho-LRP6 (Ser1490)磷酸化低密度脂蛋白受体相关蛋白6抗体
hz-3245R Phospho-LATS1 (Thr1079)磷酸化肿瘤抑制基因LATS1抗体
hz-0683R LRRK2富亮氨酸重复激酶2抗体
hz-0661R LRP肺耐药相关蛋白抗体
hz-9329R LRCH3富含亮氨酸重复家庭蛋白3抗体
hz-9466R LRRC10富含亮氨酸重复蛋白10抗体
hz-9328R LRCH2富含亮氨酸重复家庭蛋白2抗体
hz-7615R LRDD富含亮氨酸重复死亡结构域蛋白抗体
hz-0901R LAMR1(CT)层粘连蛋白受体1抗体（C端）
hz-0900R LAMR1层粘连蛋白受体1抗体（N端）
hz-9842R phospho-LEF1(Ser42)磷酸化淋巴增强因子-1抗体
hz-11351R LAP1层粘连相关多肽蛋白1抗体
hz-11175R Lubricin浅表层粘膜蛋白多糖抗体
hz-11200R LHX2调控胚胎干细胞分化蛋白Lhx2抗体
hz-8360R LRRC2LRRC2蛋白抗体
hz-11090R LRRC4B神经突触蛋白NGL3抗体
hz-9972R LCA5L致盲基因LCA5样蛋白抗体
hz-9973R LCA5致盲基因LCA5蛋白抗体
hz-7869R LHX6转录因子LHX6抗体
hz-7913R phospho-LATS1+LATS2 (Thr1079 +Thr1041)磷酸化肿瘤抑制基因LATS1/LATS2抗体
hz-11867R LBX1转录因子LBX1抗体
hz-11868R LDB1神经细胞特异性转录因子LDB1抗体
hz-11869R LECT2白细胞细胞化学吸引素2抗体
hz-11870R LHX5LHX5蛋白抗体
hz-11871R LIM kinase 1 + 2单丝氨酸蛋白激酶1+2抗体
hz-11872R LIN7CLIN7C蛋白抗体
hz-11873R LINGO4富含亮氨酸重复序列Nogo受体反应蛋白4抗体
hz-10536R LRG1富含亮氨酸α2糖蛋白抗体
hz-11875R LPPR4脑特异性磷脂酸磷酸酶样蛋白1抗体
hz-11876R LR8跨膜蛋白TMEM176B抗体