免疫原 :
Recombinant Human MOG Protein (Catalog#10364-H08E)
Antibody Type : Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
克隆号 :
013
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
This antibody was obtained from a rabbit immunized with purified, human cell-derived, recombinant Human MOG (rh MOG; Catalog#10364-H08E; NP_996532.2; Gly 30 - Tyr 149)
MOG抗体Background
Myelin oligodendrocyte glycoprotein (MOG) is a transmembrane protein belonging to immunoglobulin superfamily, and contains an Ig-like domain followed by two potential membrane-spanning regions. MOG is expressed only in the CNS with very low content (approximately 0.1% total proteins) in oligodendrogliocyte membrane. Three possible functions for MOG were suggested: (a) a cellular adhesive molecule, (b) a regulator of oligodendrocyte microtubule stability, and (c) a mediator of interactions between myelin and the immune system, in particular, the complement cascade. A direct interaction might exist between the membrane-associated regions of MOG and the myelin-specific glycolipid galactocerebroside (Gal-C), and such an interaction may have important consequences regarding the membrane topology and function of both molecules. It is considered that MOG is an autoantigen capable to produce a demyelinating multiple sclerosis-like disease in experimental animals.
MOG抗体相关产品如下:
hz-6093R RIL抑癌基因PDLIM4抗体
hz-6094R RIN1RAS抑制蛋白1抗体
hz-6101R RUNX1T1周期素D相关蛋白抗体
hz-6095R RND3Rho家族GTP酶3抗体
hz-6096R RNF139环指蛋白139抗体
hz-6098R Rho GTPase activating protein 29Rho GTP酶激活蛋白29抗体
hz-6097R RSRC2食道癌抑制生长蛋白抗体
hz-6089R RASSF8RAS家族关联结构域蛋白8抗体
hz-4282R Ran雄激素受体相关蛋白24抗体
hz-6501R Rab25癌基因RAS相关蛋白Rab25抗体
hz-6219R RXR beta核受体RXRβ抗体
hz-6218R RAR gamma维甲酸受体γ抗体
hz-4630R phospho-ROCK1(Thr455+Ser456)磷酸化Rho相关蛋白激酶1抗体
hz-6130R RbAp48视网膜母细胞瘤结合蛋白P48抗体
hz-11358R RIMBP2神经元突触膜结合蛋白2抗体
hz-11359R RIMS3神经元突触膜胞外分泌调节蛋白3抗体
hz-11360R RIMS4神经元突触膜胞外分泌调节蛋白4抗体
hz-11369R SynGAP认知缺陷突触相关蛋白SynGAP抗体
hz-11472R RSPH4AKartagener综合征相关蛋白RSHL3抗体
hz-11473R RGMA反义导向分子RGMA抗体
hz-11474R Repulsive Guidance Molecule B反义导向分子RGMB抗体
hz-11475R RGMC/Repulsive Guidance Molecule C反义导向分子RGMC抗体
hz-11476R Robo3轴突导向受体蛋白3抗体
hz-6916R RABX5G蛋白相关RABX5抗体
hz-9226R RNF157环指蛋白157抗体
hz-7518R Ribonuclease Inhibitor核糖核酸酶抑制因子1抗体
hz-2966R RBPJKNotch转录调控蛋白RBPJK抗体
hz-7028R RCAN2钙调神经磷酸酶调节蛋白2抗体(唐氏综合征候选区域蛋白1样蛋白2)
hz-6570R RING5环指蛋白5抗体(E3泛素蛋白连接酶RNF5)
hz-6571R RPL15核糖体蛋白L15抗体
hz-6569R RLBP1L1视黄醛结合蛋白1抗体
hz-6576R RBBP6视网膜母细胞瘤结合蛋白6抗体
hz-6574R RRBP1核糖体结合蛋白1抗体
hz-6573R RPL5核糖体蛋白L5抗体
hz-6581R RNA polymerase II CTD repeat YSPTSPS (phospho S2)磷酸化RNA聚合酶II CTD抗体
hz-6582R RNA polymerase II CTD repeat YSPTSPS (phospho S5)磷酸化RNA聚合酶II CTD抗体
hz-6583R RNASE4血管生成素核糖核酸酶4抗体(肌萎缩性侧索硬化症蛋白)
hz-6572R RPL19核糖体蛋白L19抗体
hz-5722R RASL10ARas样蛋白家族10A抗体
hz-5706R RASSF4Ras相关区域家族蛋白4抗体
hz-9626R RPUSD2RNA尿苷酸合酶结构域蛋白2抗体
hz-9225R RNF14环指蛋白14抗体
hz-9007R RCBTB1鸟嘌呤核苷酸交换因子抗体
hz-9653R RBFA核糖体结合因子RBFA抗体
hz-9231R RNF166环指蛋白166抗体
hz-11030R RP1视网膜色素变性蛋白1抗体