Fetuin A / AHSG抗体产品信息免疫原 : Human cell-derived rhFetuin A ( Catalog #10318-H08H )
抗体宿主 : Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : Produced in rabbits immunized with purified, human cell-derived, recombinant human Fetuin A / AHSG ( rhFetuinA; Catalog #10318-H08H; NP_001613.2; Met 1- Val 367 ). Total IgG was purified by Protein A affinity chromatography.
Fetuin A / AHSG抗体 Background
Human Fetuin A, also known as α2-Heremans-Schmid glycoprotein (AHSG), is a member of cystatin superfamily of protease inhibitors. It is expressed and secreted mainly by the cell source hepatocytes, and can be found at high levels in the serum as a growth promoter. As an antagonist of transforming growth factor-beta1 (TGF-β1), fetuin A blocks TGF-beta1 binding to cell surface receptors, suppresses TGF-beta signal transduction and epithelial-mesenchymal transition, suggesting that the systemic fetuin A is closely associated with tumor progression and resistance to chemotherapy in established cancers, as well as host immune suppression. Accordingly, therapeutic enhancement of AHSG levels may benefit patients whose tumors are driven by TGF-beta. It has been shown that fetuin A inhibits both insulin receptor autophosphorylation and undesirable calcification, and plays a role in bone development, calcium homeostasis, regulation of soft tissue calcification, and insulin sensitivity. Fetuin A / AHSG抗体相关产品如下:xy-10077R Brain2大脑蛋白2抗体 xy-7463R BATFB细胞转录激活因子抗体 xy-13606R BCL6BBCL6B抗体 xy-6648R BAP31BAP31蛋白抗体 xy-6589R BCAT2支链氨基酸转氨酶2抗体 xy-6590R Bcl2A1BCL2相关蛋白A1抗体 xy-6591R Bcl3B细胞淋巴瘤蛋白3抗体 xy-5960R B MyB转录因子MYB相关蛋白B抗体 xy-2165R beta Defensin 1防御素β1/Defensin β1抗体 xy-2472R BAFFRB细胞活化因子受体抗体 xy-2431R BAFFTNF家族B细胞激活因子抗体 xy-0912R Batroxobin蛇毒巴曲酶抗体 xy-8508R Brn-2大脑蛋白2抗体 xy-1103R CD274程序性死亡配体1抗体 xy-0673R B7H4B7-H4抗体 xy-0164R BACE1β分泌酶抗体 xy-0892R Bad相关死亡促进因子Bad抗体 xy-0127M BaxBax xy-1868R B7-DC程序性死亡配体2抗体 xy-1954R BSEP胆汁酸盐输出泵/ATP结合盒转运蛋白11抗体 xym-0390M Beta-2-MG(B2E5)β2微球蛋白抗体(单抗) xy-7552R Biglycan骨/软骨蛋白多糖1抗体 xy-9759R CAP染色体相关蛋白CAP抗体 xy-9269R BECN1L1Bcl-2同源结构域样蛋白1抗体 xy-7657R BAG6Bcl2相关抗凋亡基因6抗体 xy-9728R B4GALT7半乳糖转移酶7亚基β1,4抗体 xy-9270R BEND5BEN结构域蛋白5抗体 xy-9438R BBS5巴德-毕德氏综合征蛋白BBS5抗体 xy-9727R BIN2乳腺癌相关蛋白1抗体 xy-9492R Brain protein CG6脑蛋白CG6抗体 xy-11015R BFSP2晶状体蛋白2抗体 xy-9542R C7orf277号染色体开放阅读框27抗体 xy-8211R BCMP101乳腺癌膜相关蛋白101抗体 xy-4542R BRLF1立即早期癌基因BRLF1抗体(鼻咽癌基因)