缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : Produced in rabbits immunized with purified, human cell-derived, recombinant human TGFB1 / TGF-beta1 ( rh TGF-beta1 ; Catalog#10804-HNAH ; NP_000651.3 ; Ala 279- Ser 390 ). TGF-beta1 specific IgG was purified by human TGF-beta1 affinity chromatography.
TGF-beta1 / TGFB1抗体背景综述
Transforming growth factor beta 1 (TGF-beta1 , TGFβ1) is a member of the large transforming growth factor beta superfamily of cytokines, and serves as a multifunctional molecule performing actions in many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. TGFβ1 was first synthesized as a 390 amino acid precusor. The secreted proprotein contains 360 aa, and is cleaved into mature TGFβ1 (112 aa) and latency-associated peptide (LAP)(248 aa), which remains non-covalently linked to mature TGFβ1 rendering it inactive. TGFβ1 is synthesized by many cells, and regulates many other growth factors both in positive and negative manner. It has been shown that TGFβ1 plays an important role in controlling the immune system and shows different activities on different types of cell, or cells at different developmental stages. It is highly expressed in bone and as a potent stimulator of osteoblastic bone formation. TGFβ1 is able to cause chemotaxis, proliferation and differentiation in committed osteoblasts. TGFβ1 is also identified as a disease marker and a therapeutical target for cardiovascular disease.
TGF-beta1 / TGFB1抗体相关产品如下:xy-9167R RNF86环指蛋白86
xy-9168R RING2环指蛋白2抗体
xy-9171R RNF44环指蛋白44抗体
xy-9170R RNF40环指蛋白40抗体
xy-9173R RNF8环指蛋白8抗体
xy-6088R RASAL1RAS蛋白样激活剂1抗体
xy-2939R RASSF2Ras相关结构域蛋白质2抗体
xy-6093R RIL抑癌基因PDLIM4抗体
xy-6094R RIN1RAS抑制蛋白1抗体
xy-6101R RUNX1T1周期素D相关蛋白抗体
xy-6095R RND3Rho家族GTP酶3抗体
xy-6096R RNF139环指蛋白139抗体
xy-6098R Rho GTPase activating protein 29Rho GTP酶激活蛋白29抗体
xy-6097R RSRC2食道癌抑制生长蛋白抗体
xy-6089R RASSF8RAS家族关联结构域蛋白8抗体
xy-4282R Ran雄激素受体相关蛋白24抗体
xy-6501R Rab25癌基因RAS相关蛋白Rab25抗体
xy-6219R RXR beta核受体RXRβ抗体
xy-6218R RAR gamma维甲酸受体γ抗体
xy-4630R phospho-ROCK1(Thr455+Ser456)磷酸化Rho相关蛋白激酶1抗体
xy-6130R RbAp48视网膜母细胞瘤结合蛋白P48抗体
xy-11358R RIMBP2神经元突触膜结合蛋白2抗体
xy-11359R RIMS3神经元突触膜胞外分泌调节蛋白3抗体
xy-11360R RIMS4神经元突触膜胞外分泌调节蛋白4抗体
xy-11369R SynGAP认知缺陷突触相关蛋白SynGAP抗体
xy-11472R RSPH4AKartagener综合征相关蛋白RSHL3抗体
xy-11473R RGMA反义导向分子RGMA抗体
xy-11474R Repulsive Guidance Molecule B反义导向分子RGMB抗体
xy-11475R RGMC/Repulsive Guidance Molecule C反义导向分子RGMC抗体
xy-11476R Robo3轴突导向受体蛋白3抗体
xy-6916R RABX5G蛋白相关RABX5抗体
xy-9226R RNF157环指蛋白157抗体
xy-7518R Ribonuclease Inhibitor核糖核酸酶抑制因子1抗体
xy-2966R RBPJKNotch转录调控蛋白RBPJK抗体