IL10RB / CRFB4 / CDw210b抗体

The functional IL-10 receptor consists of two polypeptide chains, a ligand binding chain IL-10 Rα (IL-10 R1) and a signal transduction molecule known as IL-10 Rβ (IL-10 R2). Both chains of the IL-10 R are expressed on many hematopoietic cells, including lymphocytes, monocytes and neutrophils, with the IL-10 Rβ chain expressed at higher levels than the IL-10 Rα chain in most cases. Interleukin 10 receptor beta (IL-10 Rβ) , also known as CD210b and CRF2-4, is an 80-85 kDa member of the type II cytokine receptor family of proteins and contains two fibronectin type-III domains. The widely expressed IL-10 Rβ serves as a signal transducing accessory chain not only for IL-10, but also for other interleukins including IL-22, -28A, -28B and -29 (plus IL-26 in human) when complexed to the ligand-binding chains . It has been shown that the action of IL-10 delivered through its receptor can affect a variety of immune functions including inhibition of pro-inflammatory cytokine synthesis and regulation of the growth and function of B cells and antigen presenting cells. The human IL-10 Rβ shares 69% homology to its mouse counterpart in amino acid sequence. Research evidences indicated that defects in IL10RB are associated with susceptibility to hepatitis B virus infection.
IL10RB / CRFB4 / CDw210b抗体相关产品如下：xy-5826R PCDHAC1原钙粘蛋白1抗体
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xy-5734R PCGF1表观抑制因子Polycomb家族成员PCGFl蛋白抗体
xy-11133R PCDHAC2原钙粘蛋白介导的PCDHαC2受体抗体
xy-3517M PAK4小鼠抗p21激活激酶4抗体
xy-7534R PGC1 beta过氧化物酶体增殖物激活受体γ辅激活子1β抗体
xy-7535R PGC1 alpha + beta过氧化物酶体增殖物激活受体γ辅激活子1α+β抗体
xy-11788R Prion protein PrP/CD230朊病毒蛋白CD230抗体
xy-11410R Progestin Receptor Beta孕激素受体β（MPRβ）抗体
xy-11411R PTGFR前列腺素F2a受体抗体PGF2αR
xy-6350R pan methyl Lysine泛甲基赖氨酸抗体
xy-6370R p70 S6 kinase alpha核糖体p70 S6蛋白激酶抗体
xy-7094R p53AIP1p53调节凋亡诱导蛋白1抗体
xy-7101R PTRH2Bcl-2转录抑制因子1抗体
xy-7099R PLSCR3磷脂爬行酶3抗体
xy-7634R PARL骨骼肌细胞线粒体膜蛋白PARL抗体
xy-7100R PNPT1多核苷酸磷酸化酶蛋白抗体
xy-6382R PTK5胃肠道相关酪氨酸激酶抗体（蛋白酪氨酸激酶5）
xy-6392R PCNPPEST含核蛋白抗体
xy-3020R phospho-p53BP1 (Ser25 + Ser29)磷酸化p53结合蛋白1抗体
xy-3756R PP1A蛋白磷酸酶2Cα抗体
xy-3744R Phospho-Paxillin(Tyr31)磷酸化桩蛋白Paxillin抗体
xy-3806R PGP9.5神经细胞胞浆蛋白9.5抗体（蛋白基因产物9.5）
xy-4024R phospho-PKA beta(Ser338)磷酸化蛋白激酶Aβ抗体
xy-3963R PKA R2蛋白激酶A受体2α亚基抗体
xy-4022R phospho-PKA R2 (Ser96)磷酸化蛋白激酶A受体2α亚基抗体
xy-3964R PKA gamma蛋白激酶Aγ抗体
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xy-5179R phospho-PTPRA(Tyr798)磷酸化酪氨酸磷酸酶α抗体
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xy-5175R phospho-PTPRA (Ser180)磷酸化酪氨酸磷酸酶α抗体
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xy-5423R PPAP2A磷酸脂磷酸水解酶1抗体
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