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- xy11931-RP02
- 2025年07月13日
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- 技术资料
- 保存条件：
常温，避光
- 克隆性：
单克隆
- 抗体名：
Tryptophan Hydroxylase 1 / TPH1抗体
Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 : Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : Produced in rabbits immunized with purified, recombinant Human Tryptophan Hydroxylase 1 / TPH1 (rh Tryptophan Hydroxylase 1 / TPH1; Catalog#11931-H07E; P17752-1; Ile 2-Ile 444). Tryptophan Hydroxylase 1 / TPH1 specific IgG was purified by Human Tryptophan Hydroxylase 1 / TPH1 affinity chromatography.
Tryptophan Hydroxylase 1 / TPH1抗体 Background
Tryptophan 5-hydroxylase 1, also known as Tryptophan 5-monooxygenase 1, Tryptophan hydroxylase 1, TPH1, TPH and TPRH, is anenzyme which belongs to thebiopterin-dependent aromatic amino acid hydroxylase family. TPH1 contains oneACT domain. Tryptophan hydroxylase catalyzes the biopterin-dependent monooxygenation of tryptophan to 5-hydroxytryptophan (5HT), which is subsequently decarboxylated to form the neurotransmitter serotonin. It is the rate-limiting enzyme in the biosynthesis of serotonin. It is the rate-limiting enzyme in the biosynthesis of serotonin. TPH1 expression is limited to a few specialized tissues: raphe neurons, pinealocytes, mast cells, mononuclear leukocytes, beta-cells of the islets of Langerhans, and intestinal and pancreatic enterochromaffin cells.The tryptophan hydroxylase 1 (TPH1) gene is also reported to be associated with suicidal behavior. Polymorphisms of TPH1 may assist in identifying a subgroup of mood disorder patients that is at higher risk for suicidal behavior.
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文献和实验蛋白质的翻译后修饰(Post-Translational Modification,PTM)在许多细胞生命活动过程中发挥着重要作用。蛋白巴豆酰化（Lysine Crotonylation, Kcr）作为一种新发现的翻译后修饰(PTM)，由芝加哥大学赵英明教授研究团队于2011年发现，并被Cell杂志评选为当年“年度五大突破性进展”之一。继上篇《个性化修饰性抗体技术解读之泛素化抗体》之后，我们继续聊一聊巴豆酰化抗体。 什么是巴豆酰化 蛋白
Introduction of human 14-3-3 proteins
,is a dimeric protein that possesses many of the attributes of diverse mammalian 14-3-3 homologues.GF14 omega activates rat brain tryptophan hydroxylase and protein kinase C in a manner similar to the bovine 14-3-3 protein.It also activates exoenzyme S
[资源] 所有的看家基因(housekeeping genes)列表+引物设计服务
endothelial growth factor B (VEGFB ), mRNA 649 NM_003576 Homo sapiens serine/threonine kinase 24 (STE20 homolog, yeast) (STK24), mRNA 769 NM_000918 Homo sapiens procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide
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