Coagulation Factor IX / F9抗体

Coagulation Factor IX / F9抗体产品信息免疫原 : Recombinant Human Coagulation Factor IX / F9 protein (Catalog#11503-H08H)

Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 : Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : Produced in rabbits immunized with purified, recombinant Human Coagulation Factor IX / F9 (rh Coagulation Factor IX / F9; Catalog#11503-H08H; AAB59620.1; Met 1-Thr 461). Coagulation Factor IX / F9 specific IgG was purified by Human Coagulation Factor IX / F9 affinity chromatography.
Coagulation Factor IX / F9抗体 Background
Coagulation factor IX, also known as Christmas factor, Plasma thromboplastin component and PTC, is a secreted protein which belongs to thepeptidase S1 family. Coagulation factor IX / F9 contains two EGF-like domains, one Gla (gamma-carboxy-glutamate) domain and one peptidase S1 domain. Coagulation factor IX / F9 is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca2+ions, phospholipids, and factor VIIIa. Defects in Coagulation factor IX / F9 are the cause of thrombophilia due to factor IX defect which is a hemostatic disorder characterized by a tendency to thrombosis.Defects in Coagulation factor IX / F9 are also the cause of recessive X-linked hemophilia B (HEMB) which also known as Christmas disease.
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