TNFRSF11A抗体

TNFRSF11A抗体产品信息免疫原 : Recombinant Rat TNFRSF11A protein (Catalog#80160-R08H)

Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 : Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : Produced in rabbits immunized with purified, recombinant Rat TNFRSF11A (rR TNFRSF11A; Catalog#80160-R08H; XP_573424.2; Met1-Pro213). Total IgG was purified by Protein A affinity chromatography.
TNFRSF11A抗体 Background
TNFRSF11A, also known as CD265, contains 4 TNFR-Cys repeats and belongs to the TNF-receptor superfamily. TNFRSF11A has an ubiquitous expression with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. TNFRSF11A can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. TNFRSF11A and its ligand are important regulators of the interaction between T cells and dendritic cells. It is also an essential mediator for osteoclast and lymph node development. Defects in TNFRSF11A are the cause of familial expansile osteolysis (FEO). FEO is a rare autosomal dominant bone disorder characterized by focal areas of increased bone remodeling. Defects in TNFRSF11A also can cause Paget disease of bone type 2 (PDB2). PDB2 is a bone-remodeling disorder with clinical similarities to FEO. Defects in TNFRSF11A are the cause of osteopetrosis autosomal recessive type 7 which characterized by abnormally dense bone, due to defective resorption of immature bone.
TNFRSF11A抗体相关产品如下：xy-5155R phospho-LSP1 (Ser204)磷酸化白细胞F肌动蛋白结合蛋白抗体
xy-4082R phospho-LATS2 (Ser83)磷酸化肿瘤抑制基因LATS2抗体
xy-5156R phospho-LSP1 (Ser252)磷酸化白细胞F肌动蛋白结合蛋白抗体
xy-5154R LSP1白细胞F肌动蛋白结合蛋白抗体
xy-5138R LZTFL1亮氨酸拉链转录因子样1抗体
xy-5122R Laminin B2 gamma 1层粘连蛋白B2γ1抗体
xy-10127R Phospho-LAT (Tyr161)磷酸化T细胞活化连接蛋白抗体
xy-10128R Phospho-LAT (Tyr200)磷酸化T细胞活化连接蛋白抗体
xy-2677R LRP1/CD91低密度脂蛋白受体相关蛋白1抗体
xy-12446R LPCAT2磷脂酰基转移酶2抗体
xy-12438R LRRFIP2LRRFIP2蛋白抗体
xy-12439R LRRFIP1巨噬细胞调控相关蛋白LRRFIP1抗体
xy-0951R LH beta促黄体生成素抗体
xy-5951R LIMS1整合素和生长因子样蛋白1抗体
xy-4771R LLGL2相似肿瘤抑制基因HUGL抗体
xy-13687R LAMTOR1LAMTOR1蛋白抗体
xy-13649R LDB3LIM结构域结合蛋白3抗体
xy-13650R LIMS2ILK结合蛋白LIMS2抗体
xy-13651R LNK淋巴细胞特异性接头蛋白抗体
xy-7349R LILRB2细胞表面免疫球蛋白样转录因子4抗体
xy-13652R LY6G6F淋巴细胞抗原6重复位点蛋白G6F抗体
xy-13653R Leupaxin桩蛋白抗体
xy-6055R LRPAP1脂蛋白受体相关蛋白/低密度脂蛋白相关蛋白的相关蛋白1抗体
xy-6068R LEPREL2皮屑样蛋白2抗体
xy-1969R LAMA3层粘蛋白α3抗体
xy-1970R LAMP1溶酶体相关膜蛋白1抗体
xy-1971R Lxn/Latexin羧肽酶抑制剂抗体
xy-1972R LCAT卵磷酯胆固醇酰基转移酶抗体
xy-1973R LPL/PLASTIN2脂蛋白脂酶抗体
xy-0961R Leptin receptor瘦素受体抗体
xy-2905R LRP6低密度脂蛋白受体相关蛋白6抗体
xy-3253R Phospho-LRP6 (Ser1490)磷酸化低密度脂蛋白受体相关蛋白6抗体
xy-3245R Phospho-LATS1 (Thr1079)磷酸化肿瘤抑制基因LATS1抗体