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- xy10483-RP02
- 2025年07月10日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
常温，避光
- 克隆性：
单克隆
- 抗体名：
Cathepsin B / CTSB抗体
Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 : Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : Produced in rabbits immunized with purified, human cell-derived, recombinant Human Cathepsin B / CTSB (rh Cathepsin B / CTSB; Catalog #10483-H08H; NP_001899.1). Cathepsin B / CTSB specific IgG was purified by Human Cathepsin B / CTSB affinity chromatography.
Cathepsin B / CTSB抗体 Background
Human Cathepsin B (CTSB) is a papain-family cysteine protease that is normally located in lysosomes, and is a member of a superfamily of structurally similar tissue proteinases having a 25 kDa catalytic unit. Cathepsin B is synthesized as a preproenzyme and the primary pathways for its normal trafficking to the lysosome utilize mannose 6-phosphate receptors (MPRs). Mature cathepsin B has the ability to degrade several extracellular matrix components at both neutral and acidic pH and has been implicated in the progression of several human and rodent tumors progression and arthritis. Overexpression and altered trafficking of cathepsin B characterize the malignant phenotype of tumor cells, and thus CTSB is suggested as a tumor marker.
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Detection of Hepatitis B Virus X Antigen by Immunohistochemistry and Western Blotting
The genome of hepatitis B virus (HBV) is a partially double-stranded DNA molecule within virus particles that is approx 3.2 kbp long (1 ,2 ). It has four open reading frames, all on one strand, that encode the surface antigen or envelope
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