TEM7 / PLXDC1抗体

TEM7 / PLXDC1抗体产品信息免疫原 : Recombinant Human TEM7 / PLXDC1 protein (Catalog#11736-H08H)

Antibody Type : Mouse Monoclonal Antibody ( Mouse mAb Service Platform )
克隆号 : 05
抗体宿主 : Mouse IgG1
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TEM7 / PLXDC1 (rh TEM7 / PLXDC1; Catalog#11736-H08H; AAH36059.1; Met 1-Thr 426). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
TEM7 / PLXDC1抗体 Background
Plexin domain-containing protein 1, also known as tumor endothelial marker 3, tumor endothelial marker 7 and PLXDC1 and TEM3, is a secreted, cytoplasm and single-pass type I membrane protein which belongs to theplexin family. PLXDC1 / TEM3 is detected in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. It is expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy. PLXDC1 / TEM3 is not detectable in endothelial cells from normal tissue. PLXDC1 / TEM3 plays a critical role in endothelial cell capillary morphogenesis. PLXDC1 / TEM3 may play a significant role in the proliferation and maintenance of neovascular endothelial cells in the formation of fibrovascular membranes (FVMs). PLXDC1 / TEM3 may be a molecular target for new diagnostic and therapeutic strategies for proliferative diabetic retinopathy (PDR). PLXDC1 / TEM3 interacts with NID1. It may also interact with CTTN.
TEM7 / PLXDC1抗体相关产品如下：xy-1363R AIF1离子钙接头蛋白抗体
xy-9464R IRX4Iroquois同源蛋白4抗体
xy-6877R IFRD1干扰素相关发育调节蛋白1抗体（神经生长因子诱导蛋白PC4）
xy-6870R ILP2抑制细胞凋亡样蛋白2抗体
xy-4750R IFITM1干扰素诱导跨膜蛋白1抗体
xy-8690R IFI44干扰素诱导蛋白44抗体
xy-6471R ITPR35-三磷酸肌醇受体3抗体
xy-15525R IFNW1干扰素omega 1蛋白抗体
xy-15521R IFNA7干扰素alpha 7蛋白抗体
xy-0787R IFN-Beta干扰素β抗体
xy-3529R ID1DNA结合抑制因子1抗体
xy-8676R IFI-202γ干扰素诱导蛋白202抗体
xy-0788R intestinal FABP/IFABP/FABP2肠型脂肪酸结合蛋白抗体
xy-1291R ING1生长抑制因子基因1抗体
xy-0780R IL-8/CXCL8白介素8抗体
xy-0317R ILK-1整合素连接激酶-1抗体
xy-3235R phospho-IKK alpha (Ser176 + Ser180)磷酸化KB抑制蛋白激酶α抗体
xy-3236R Phospho-IKK alpha(Ser180) + IKK beta(Ser181)磷酸化KB抑制蛋白激酶α/β抗体
xy-3237R Phospho-IKK alpha/beta (Ser176 + Ser180)磷酸化KB抑制蛋白激酶α/β抗体
xy-15563R IFT46细胞纤毛内转运同源蛋白46抗体
xy-2459R IL-10RA白细胞介素-10受体a抗体
xy-2460R IL-13Ra1白细胞介素-13受体a1抗体
xy-4015R IRGM免疫相关鸟苷三磷酸酶基因抗体
xy-2461R IL-13Ra2白细胞介素-13受体a2抗体
xy-2450R I-309嗜酸粒细胞趋化蛋白CCL1抗体
xy-3226R phospho-IGF1R (Tyr1161)磷酸化胰岛素样生长因子1受体抗体
xy-0018R IDE胰岛素降解酶抗体
xy-1789R IL-12白介素12抗体
xy-1740R IL-4白介素4抗体
xy-6059R IGFBP9胰岛素样生长因子结合蛋白9抗体
xy-2710R IFNGR2干扰素-gamma受体2抗体
xy-2711R IL-27R白细胞介素27受体抗体
xy-2216R IL-1RA白介素-1受体拮抗剂抗体
xy-2898R IKK gammaKB抑制蛋白激酶γ抗体
xy-3227R phospho-IKK gamma (Ser85)磷酸化KB抑制蛋白激酶γ抗体
xy-3228R phospho-IKK gamma (Ser31)磷酸化KB抑制蛋白激酶γ抗体