E-Selectin / CD62e / SELE抗体

E-Selectin / CD62e / SELE抗体产品信息免疫原 : Recombinant Rat E-Selectin / CD62e / SELE protein (Catalog#80033-R08H)

Antibody Type : Mouse Monoclonal Antibody ( Mouse mAb Service Platform )
克隆号 : 01
抗体宿主 : Mouse IgG1
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat E-Selectin / CD62e / SELE (rR E-Selectin / CD62e / SELE; Catalog#80033-R08H; P98105-1; Met 1-Pro 494). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
E-Selectin / CD62e / SELE抗体 Background
E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) and CD62E, is an inducible adhesion molecule that is expressed at relatively high density on the surface of cultured endothelial cells that have been activated by proinflammatory cytokines, such as IL-1β, TNF-α, or bacterial endotoxin. E-Selectin/CD62e exhibits a complex mosaic structure consisting of a large extracellular region comprised of a lectin domain, an EGF-like domain, and a short consensus repeat (SCR) domain, followed by a transmembrane region and a relatively short (32 aa) cytoplasmic tail. As a member of the LEC-CAM or selectin family, E-Selectin/CD62e recognises and binds to sialylated carbohydrates including members of the Lewis X and Lewis A families found on monocytes, granulocytes, and T-lymphocytes. E-Selectin/CD62e supports rolling and stable arrest of leukocytes on activated vascular endothelium, and furthermore, it was indicated that it can also transduce an activating stimulus via the MAPK cascade into the endothelial cell during leukocyte adhesion. In addition, this adhesion molecule appears to be involved in the pathogenesis of atherosclerosis.
E-Selectin / CD62e / SELE抗体相关产品如下：xy-9022R IQCGIQCG蛋白抗体
xy-9023R IQCKIQCK蛋白抗体
xy-6541R Id1DNA结合抑制因子1抗体
xy-6256R IMPDH1肌苷单磷酸脱氢酶1抗体
xy-6653R IFI78干扰素诱导蛋白P78抗体
xy-6686R ICAM5细胞间粘附分子5抗体
xy-6248R IMPAD1肌醇单磷酸酶IMPA3抗体
xy-5791R Integrin Alpha V + Beta 6整合素αVβ6抗体
xy-6759R IL-11RA白介素11受体α/IL-11Rα抗体
xy-11013R ILDR1免疫球蛋白样结构域受体1抗体
xy-10123R IKK Alpha + IKK betaKB抑制蛋白激酶α/β抗体 IKK α/IKK β
xy-7023R Interferon alpha 11干扰素α11抗体
xy-7024R IFNA10干扰素α10抗体
xy-7022R IFNAR2干扰素α受体2抗体
xy-7021R IFNA21干扰素α21抗体
xy-6304R IFNA4干扰素α4抗体
xy-6330R Interferon alpha 16干扰素α16抗体
xy-7018R ITIH1衍生透明质酸相关蛋白抗体
xy-7048R INPPL1肌醇聚磷酸盐磷酸酶样蛋白1抗体
xy-6625R Insig2胰岛素诱导基因2抗体
xy-6624R IHHHHG2抗体
xy-7020R Interferon alpha 17干扰素α17抗体
xy-11855R IL1RAPL2白介素1受体9抗体
xy-11856R IQGAP3RasGTP酶激活蛋白IQGAP3抗体
xy-11857R IRX1Iroquois同源蛋白1抗体
xy-11858R ITM2B跨膜蛋白BRI抗体
xy-11859R ITM2C跨膜蛋白ITM2C抗体
xy-10069R IL-31白细胞介素31抗体
xy-0474R human Serum IgA人血清型免疫球蛋白A抗体
xy-7867R Iroquois homeobox protein 3Irx3蛋白抗体
xy-7866R Intra Acrosomal Protein精子顶端体蛋白10抗体
xy-4964R human secretory IgA人分泌型免疫球蛋白A
xy-11349R ICA1胰岛细胞自身抗原1抗体
xy-11321R Islet 2胰岛素基因增强结合蛋白2抗体
xy-0768R IL-16白介素-16抗体