CD9抗体

CD9抗体产品信息免疫原 : Recombinant Human CD9 protein (Catalog#11029-H08H)

Reagents : FITC-conjugated mouse monoclonal antibody
Clone ID : 01
抗体宿主 : Mouse IgG1
Concentration : 10 μl/Test, 0.1 mg/ml
缓冲液 : Aqueous solution containing 0.5% BSA and 0.09% sodium azide
制备方法 : This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD9 (rh CD9; Catalog#11029-H08H; NP_001760.1; Ser 112-Ile 195) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
CD9抗体 Background
CD9 antigen, also known as 5H9 antigen, cell growth-inhibiting gene 2 protein, leukocyte antigen MIC3, motility-related protein, tetraspanin-29, CD9 and MIC3, is a multi-pass membrane protein which belongs to thetetraspanin (TM4SF) family. It is a cell surface marker expressed on myeloid and nonmyeloid as well as on neoplastic cells. CD9 forms both disulfide-linked homodimers and higher homooligomers as well as heterooligomers with other members of the tetraspanin family. Numerous functions have been attributed to CD9 and other members of the transmembrane 4 (TM4) superfamily. CD9 is thought to be involved in cell proliferation, differentiation, motility and survival. It may also function as part of toxin and virus receptor complexes. CD9 is involved in platelet activation and aggregation. It regulates paranodal junction formation and is involved in cell adhesion, cell motility and tumor metastasis. CD9 is required for sperm-egg fusion. CD9 associates with CR2/CD21 and with PTGFRN/CD9P1. It interacts directly with IGSF8.
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