CD3D / CD3 Delta Chain抗体

CD3D / CD3 Delta Chain抗体产品信息免疫原 : Recombinant human CD3D protein ( Catalog#10981-H08H )

Antibody Type : Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
克隆号 : 6
抗体宿主 : Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : This antibody was obtained from a rabbit immunized with purified, human cell-derived, recombinant human CD3D ( rh CD3D ; Catalog#10981-H08H ; NP_000723.1 ; Met 1 - Ala 105 ).
CD3D / CD3 Delta Chain抗体背景综述
T-cell surface glycoprotein CD3 delta chain, also known as CD3D, is a single-pass type I membrane protein. CD3D, together with CD3-gamma, CD3-epsilon and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. This complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. The T cell receptor-CD3 complex is unique in having ten cytoplasmic immunoreceptor tyrosine-based activation motifs (ITAMs). CD3D contains 1 ITAM domain and has been shown to interact with CD8A. Defects in CD3D cause severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (T-/B+/NK+ SCID) which is a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels.
CD3D / CD3 Delta Chain抗体相关产品如下：xy-3401R phospho-PYK2 (Tyr881)磷酸化富含脯氨酸的酪氨酸激酶2抗体
xy-3362R Phospho-p90RSK (Ser380)磷酸化丝氨酸/苏氨酸激酶p90RSK蛋白抗体
xy-3363R Phospho-p90RSK (Thr359 + Ser363)磷酸化丝氨酸/苏氨酸激酶p90RSK蛋白抗体
xy-3364R Phospho-p90RSK (Thr573)磷酸化丝氨酸/苏氨酸激酶p90RSK蛋白抗体
xy-1828R Plasminogen纤维蛋白溶酶原抗体
xy-1995R p95 NBS1DNA修复蛋白NBS1抗体
xy-2512R PRMT1蛋白质精氨酸甲基转移酶1抗体
xy-2589R P450 1A2/CYP1A2细胞色素P450 1A2抗体
xy-3460R Phospho-PLC gamma 1 (Tyr771)磷酸化磷酯酶Cγ1抗体
xy-3342R Phospho-PLC gamma 1(Ser1248)磷酸化磷酯酶Cγ1抗体
xy-3343R Phospho-PLC γ1 (Tyr783)磷酸化磷酯酶Cγ1抗体
xy-3345R Phospho-PLK1 (Ser137)磷酸化丝/苏氨酸蛋白激酶Plk1抗体
xy-3355R Phospho-PNK1 (Ser114 + Thr118)磷酸化多聚合苷酸激酶3磷酸化酶抗体
xy-3538R PSD93突触后密度蛋白93抗体
xy-3348R Phospho-PSD93 (Tyr340)磷酸化突触后密度蛋白93抗体
xy-3349R Phospho-PSD95 (Tyr236 + Tyr240)磷酸化突触后密度蛋白95抗体
xy-3350R Phospho-PTEN(Ser380)磷酸化肿瘤抑制基因PTEN抗体
xy-3351R Phospho-PTEN(Ser380 + Thr382 + Thr383)磷酸化肿瘤抑制基因PTEN抗体
xy-3539R Paxillin桩蛋白Paxillin抗体
xy-3352R Phospho-Paxillin (Tyr118)磷酸化桩蛋白Paxillin抗体
xy-3540R PIM1丝氨酸/苏氨酸激酶蛋白Pim1抗体
xy-3353R Phospho-PIM1(Tyr218)磷酸化前病毒整合位点蛋白1抗体
xy-3541R Pin1肽基脯氨酞顺反异构酶Pinl抗体
xy-3354R Phospho-Pin1 (Ser16)磷酸化肽基脯氨酞顺反异构酶Pinl抗体
xy-3356R Phospho-Progesterone Receptor(Ser190)磷酸化孕激素受体抗体
xy-6417R phospho-PI3 Kinase p110 beta(Ser1070)磷酸化磷脂酰肌醇激酶（PI3Kβ）抗体
xy-6418R phospho-PP2A alpha (Tyr307)磷酸化蛋白磷酸酶2A（PP2Aα）抗体
xy-7918R PLK5丝氨酸/苏氨酸蛋白激酶5抗体
xy-7898R PICK1蛋白激酶Cα相互作用蛋白1抗体
xy-8065R PID1磷酸相互作用结构域蛋白1抗体
xy-7931R PPP2R1A蛋白质磷酸酶2调节亚基1A抗体
xy-7932R PPP2R1B蛋白质磷酸酶2调节亚基1B抗体
xy-7933R PPP2R3A蛋白质磷酸酶2调节亚基3A抗体