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- 详细信息
- 文献和实验
- 技术资料
- 克隆性:
多克隆
- 抗体英文名:
CD3d Antibody [T3D; T-cell surface glycoprotein CD3 delta chain; T-cell receptor T3 delta chain; CD3d]
- 规格:
50 ul
产品名称:CD3d抗体|CD3d Antibody [T3D; T-cell surface glycoprotein CD3 delta chain; T-cell receptor T3 delta chain; CD3d]
【产品形式】:艾美捷为您提供的CD3d抗体为无色溶液形式,产品浓度为1 mg/ml,溶解于0.42% 磷酸钾, 0.87% 氯化钠, pH 7.3, 30%甘油,和0.01% NaN3的缓冲液中.请在收到该CD3d抗体产品后,将其置于-20 °C冷冻保存,建议分装使用以避免反复冻融.
【背景资料】:T-cell surface glycoprotein CD3 delta chain, also known as CD3D, is a single-pass type I membrane protein. CD3D, together with CD3-gamma,CD3-epsilon and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. This complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. The T cell receptor-CD3 complex is unique in having ten cytoplasmic immunoreceptor tyrosine based activation motifs (ITAMs). Defects in CD3D cause severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK cell-positive (T-/B+/NK+SCID) which is a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels.
BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的领导者.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有 卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代 谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理, 艾美捷与BioVision一起为研究者们提供最好、最新的细胞生物学研究工具而不断扩大产品及服务质量.
点击:CD3d抗体,查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。
关键词:CD3d,CD3d抗体
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文献和实验Cell Surface Immunofluorescence Staining Protocol
as the antibodies used for immunofluorescent staining. 4. Cell-Surface Staining with Antibody: Add appropriately conjugated fluorescent, biotinylated, or purified primary antibodies at predetermined optimum concentrations (e.g. anti-CD3-FITC, anti
Using Bioinformatics Tools for the Sequence Analysis of Immunoglobulins and T Cell Receptors
. Lafaille, J.J., DeCloux, A., Bonneville, M., Takagaki, Y., and Tonegawa, S., 1989. Junctional sequences of T cell receptor gamma delta genes: Implications for gamma delta T cell lineages and for a novel
The OP9-DL1 System: Generation of T-Lymphocytes from Embryonic or Hematopoietic Stem Cells In Vitro
, Totowa, NJ. La Motte-Mohs, R.N., Herer, E., and Zúñiga-Pflücker, J.C. 2005. Induction of T-cell development from human cord blood hematopoietic stem cells by Delta-like 1 in vitro. Blood 105: 1431439.[Abstract/Free Full Text] Nagy
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