MMP-24/MT5-MMP/MMP-21 Antibody
Cat#:PL0304145
Isotype:Rabbit Polyclonal IgG
Immunogen:Peptide derived from human MMP24.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted.
Alternate Names:
Matrix metallopeptidase 24 (membrane inserted); Matrix metallopeptidase 24; Membrane type 5 matrix metalloproteinase; Membrane type matrix metalloproteinase 5; Membrane-type matrix metalloproteinase 5; Membrane-type-5 matrix metalloproteinase; MMP 24; MMP 25; MMP-24; Mmp24; MMP24_HUMAN; MMP25; MT MMP5; MT-MMP 5; MT5 MMP; MT5-MMP; MT5MMP; MTMMP5; Processed matrix metalloproteinase-24.
Specificity Reaction:Hu, Mo, Rat, Chi, Cow, Hor,
Application Notes:WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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