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Recombinant Human MUTED/Recombinant Human MUTED
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- 保存条件:
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- 英文名:
Recombinant Human KISS-1 Metastasis-Suppressor
- 库存:
100
- 供应商:
艾美捷科技
- 规格:
10ug///1mg///2ug
【KISS1】重组KISS-1肿瘤转移抑制蛋白,Recombinant Human KISS-1 Metastasis-Suppressor,KISS1
产品名称:【KISS1】重组KISS-1肿瘤转移抑制蛋白-Recombinant Human KISS-1 Metastasis-Suppressor 产品货号:PRO-419 产品规格:10ug///1mg///2ug 来源宿主:大肠杆菌中重组表达
保存建议:【KISS1】重组KISS-1肿瘤转移抑制蛋白-Recombinant Human KISS-1 Metastasis-SuppressorKISS1 although stable 4℃ for 4 weeks, should be stored desiccated below -18℃.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
背景资料:KISS1 is a metastasis suppressor protein that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity.KISS1 functions to inhibit chemotaxis and invasion, attenuating metastasis in malignant melanomas. KISS1 is involved in the regulation of cell-matrix adhesion. KISS1 plays a role in cytoskeletal reorganization. A polymorphism in the terminal exon of KISS1 mRNA results in two protein isoforms. Expression of KiSS1 is localized to specific regions of the hypothalamus in numerous species and is regulated by gonadal steroids and across the estrous cycle..KISS1 generates a c-terminally amidated peptide, metastin which functions as the endogenous ligand of the g-protein coupled receptor gpr54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis.
点击:【KISS1】重组KISS-1肿瘤转移抑制蛋白-Recombinant Human KISS-1 Metastasis-Suppressor查看更详细产品说明,更多应用、储存、价格、货期等信息请致电垂询艾美捷科技有限公司。更多prospec公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
ProSpec 是一家全球著名细胞因子蛋白生产和研发的公司,具有20多年的生产经验,专注于蛋白(重组及合成)生产研发。我们的核心产品包括:干扰素、白介素、骨蛋白、肿瘤坏死因子、成纤维生长因子、瘦素、干细胞因子、催乳素、表皮生长因子、胰岛素样生长因子、神经生长因子、集落刺激因子、激素、酶、病毒抗原以及各种重组蛋白等。领先的生产工艺和规模使其可以提供毫克到克级蛋白,价格优于同类公司。绝大部分产品是天然成熟型蛋白,而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液,ProSpec-Tany绝大部分产品没有添加保护剂或盐,这就对工艺提出了更高的要求。同时,ProSpec-Tany绝大部分产品为冻干粉,因此易于运输和保存。
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文献和实验In Vivo Models of Human Prostate Cancer Bone Metastasis
(1 ). Much of the morbidity and mortality associated with prostate cancer is the result of its progression to distant metastasis, particularly to bone: more than 70% of patients present at autopsy with bone metastases (2 ,3 ). These lesions are usually osteoblastic
Galectin-3 Binding and Metastasis
in transformed and metastatic cell lines (Raz and Lotan Cancer Metastasis Rev 6: 433–452, 1987; Raz et al. Int J Cancer 46: 871–877, 1990). Moreover, in many human carcinomas, an increased expression of galectin-3 correlates with progressive tumor stages (Lotan
Genetic Strategies in Saccharomyces cerevisiae to Study Human Tumor Suppressor Genes
Baker’s yeast or Saccharomyces cerevisiae is the most intensely studied eukaryotic microorganism for very good reasons. Many fundamental processes such as cell cycle control and DNA repair show evolutionary conservation from yeast to human
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