Genetic Strategies in Saccharomyces cerevisiae to Study Human Tumor Suppressor Genes
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Baker’s yeast or Saccharomyces cerevisiae is the most intensely studied eukaryotic microorganism for very good reasons. Many fundamental processes such as cell cycle control and DNA repair show evolutionary conservation from yeast to human, thus making studies in yeast highly relevant to our understanding of mammalian cells. Yeast also allows for the efficient pursuit of questions that are often almost impossible to answer in mammalian assay systems.
