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- 英文名:
Recombinant Human LEC/NCC-4 (CCL16)
- 库存:
100
- 供应商:
艾美捷科技
- 规格:
1mg///20ug///5ug
【CCL16】重组人肝细胞表达趋化因子,Recombinant Human LEC/NCC-4 (CCL16),CCL16
产品名称:【CCL16】重组人肝细胞表达趋化因子-Recombinant Human LEC/NCC-4 (CCL16) 产品货号:CHM-237 产品规格:1mg///20ug///5ug 来源宿主:大肠杆菌中重组表达
保存建议:【CCL16】重组人肝细胞表达趋化因子-Recombinant Human LEC/NCC-4 (CCL16)人肝细胞表达趋化因子(CCL16)冻干粉末在室温可保存3周,或置于-18℃冻存用于长期保存.重新溶解后可以在4℃冷藏保存至少2-7天;如果想延长保存时间,建议分装(加载体蛋白如0.1% HSA或 BSA)后置于-18℃冻存.请避免反复冻融.
背景资料:Human CCL16, also called HCC-4, liver-expressed chemokine (LEC), and lymphocyte and monocyte chemoattractant (LMC), is a novel CC chemokine recognized by bioinformatics. NCC-4 cDNA encodes a 120 amino acids along with a 23 amino acids signal peptide that is cleaved to generate 97 amino acid protein. HCC4 is vaguely related to other CC chemokines, showing less than 30% sequence identity. Among CC chemokines, CCL-16 has the largest similarity to HCC-1. 2 potential polyadenylation signals are present on the human HCC-4 gene, and as a result, 2 transcripts containing roughly 1,500 base pairs and 500 base pairs have been detected. HCC-4 is expressed weakly by some lymphocytes, including NK cells, T cells, and some T cell clones. The expression of HCC-4 in monocytes is greatly upregulated in the presence of IL-10.CCL16 shows chemotactic activity for lymphocytes and monocytes rather than to neutrophils. NCC-4 has potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. CCL16 demonstrates chemotactic activity for monocytes and thp-1 monocytes, rather than for resting lymphocytes and neutrophils. HCC-4 induces a calcium flux in thp-1 cells that desensitized prior to the expression of rantes.
点击:【CCL16】重组人肝细胞表达趋化因子-Recombinant Human LEC/NCC-4 (CCL16)查看更详细产品说明,更多应用、储存、价格、货期等信息请致电垂询艾美捷科技有限公司。更多prospec公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
ProSpec 是一家全球著名细胞因子蛋白生产和研发的公司,具有20多年的生产经验,专注于蛋白(重组及合成)生产研发。我们的核心产品包括:干扰素、白介素、骨蛋白、肿瘤坏死因子、成纤维生长因子、瘦素、干细胞因子、催乳素、表皮生长因子、胰岛素样生长因子、神经生长因子、集落刺激因子、激素、酶、病毒抗原以及各种重组蛋白等。领先的生产工艺和规模使其可以提供毫克到克级蛋白,价格优于同类公司。绝大部分产品是天然成熟型蛋白,而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液,ProSpec-Tany绝大部分产品没有添加保护剂或盐,这就对工艺提出了更高的要求。同时,ProSpec-Tany绝大部分产品为冻干粉,因此易于运输和保存。
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文献和实验Immortalization of Human Prostate Cells With the Human Papillomavirus Type 16 E6 Gene
. With the addition of DU145 the list of human experimental prostate cell systems is almost exhausted, although recently new sets of cell lines, immortalized by viral and nonviral genes, have begun to appear to augment the list (1 –5 ).
三句话读懂一篇 CNS:过度午睡会增加痴呆风险?低碳水饮食或导致男士性功能障碍
杂志发表研究论文 CCL5 confines liver regeneration by downregulating reparative macrophage-derived HGF in an FoxO3a dependent manner。 该研究将 C-C 基序趋化因子配体 (CCL) 5 鉴定为肝脏再生的重要负调节因子,发现通过 FoxO3a 途径增强修复性巨噬细胞的 HGF 分泌,抑制 CCL5 能极大地优化了小鼠存活并促进了肝脏再生! 图 7:来源 Hepatology
16 Quantification of Gene Expression in Mouse and Human Renal Proximal Tubules
The kidney consists of many functional modules called nephrons. Each nephron has a tubular structure made up of several structurally and functionally distinct segments. The analysis of individual segments requires the use of microdissection
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