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- 详细信息
- 文献和实验
- 技术资料
- 克隆性:
多克隆
- 抗体英文名:
GFRalpha-1 Antibody,Glial cell line derived neurotrophic factor,GDNF,GFR alpha,GFR a,GFR-alpha,GFR-a
- 规格:
100 ug
产品名称:GFRalpha-1抗体|GFRalpha-1 Antibody,Glial cell line derived neurotrophic factor,GDNF,GFR alpha,GFR a,GFR-alpha,GFR-a
【产品形式】:艾美捷为您提供的GFRalpha-1抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA, 0.01%硫柳汞的PBS (pH 7.2)缓冲液中.请将该GFRalpha-1抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.
【背景资料】:Glial cell line-derived neurotrophic factor (GDNF) is a potent survival factor for central and peripheral neurons and is essential for the development of kidneys and the enteric nerves system. Physiological responses to GDNF require the presence of a novel glycosylphosphadidylinositol linked protein GDNFRα, which is a cell surface receptor for GDNF. The cDNA encoding GDNFRα from human, rat, chicken and mouse have been cloned recently. GDNFRα was also termed Ret ligand 1 (RETL1) or TGF-β-related neurotrophic factor receptor 1 (TrnR1) and nominated as GFRα-1 recently. GFRα-1 binds GDNF specifically and mediates activation of the Ret protein tyrosine kinase (PTK). Thus, GDNF, GFRα and the Ret PTK from a complex to transduce GDNF signal and to mediate GDNF function.
BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的领导者.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有 卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代 谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理, 艾美捷与BioVision一起为研究者们提供最好、最新的细胞生物学研究工具而不断扩大产品及服务质量.
点击:GFRalpha-1抗体,查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。
关键词:GFR,GFRalpha-1抗体
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文献和实验Culture of Purified Glial Cell Populations from Optic Nerve
Glial cells play a key role in nervous system function, providing neurotrophic factor support to neurons as well as taking part in two-way neuron-glia signaling (e.g., neurotransmitter release). White matter-derived glia are important
Expression of Neurotrophic Factors such as GDNF in the E. coli System
neurotrophic factor (BDNF), neurotrophin-3 (NT-3), NT-4/5, glial-cell-line-derived neurotrophic factor (GDNF), ciliary neurotrophic factor (CNTF), insulin-like growth factor-1 (IGF-I), are currently in clinical trials and have potential
Evaluation of Immunogenicity of Rat ES-Cell Derived Endothelial Cells
rat endothelial cells (EC). In a first characterization step, the endothelial nature of rat ES cell derived endothelial cells was proved by labelling with von Willebrand factor (vWF) as well as testing tube formation capacity on an extracellular matrix
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