【产品形式】:艾美捷为您提供的LDLR抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该LDLR抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.
【背景资料】:Low density lipoprotein receptors (LDLR) are cell surface glycoproteins that regulate LDL cholesterol by scavenging LDL from the blood. LDLR is characterized by a cluster of cysteine-rich class A repeats, EGF-like repeats, the O-linked sugars domain and six YWTD or class B repeats. Mutations in the LDLR gene cause autosomal dominant disease such as familial hypercholesterolemia (FH) and atherosclerosis.