泛素蛋白 propargylamide (TAMRA) |

【产品形式】：艾美捷为您提供的泛素蛋白 propargylamide (TAMRA)形式为Lyophilised. Dissolve initially in minimal volume of DMSO then dilute in required aqueous buffer.

【背景资料】：Ubiquitin propargylamide (Ub-PA) is a newly developed potent and specific deubiquitinating enzyme (DUB) inhibitor, N-terminally TAMRA labelled. Acts as a DUB active site specific probe facilitating detection of DUBs in biological samples. Utility in the stabilisation of ubiquitin conjugates in cell lysates and tissue extracts and as a control inhibitor for the testing and characterisation of potential DUB activity modulators. Ub-PA possess two unique capabilities: 1) Forms a covalent linkage with (the active site Cys residue of) a DUB that can be cleaved by acid treatment (5% aq. TFA), allowing for proteomic analyses 2) Targets all three major DUB families: UCH, USP and OTU TAMRA-Ub-VME probe allows detection of DUB labeling by in-gel fluorescence. This direct and more sensitive read-out gives more distinct labelling paterns than can be achieved by immunoblotting. In addition, use of TAMRA-Ub-VME removes the potential for cross-reactivity of antibodies that can lead to background labeling.

英国Viva Bioscience公司是一家研发、生产并销售蛋白降解相关产品的公司。其产品主要用于细胞自噬、泛素化和蛋白酶体研究（也覆盖其他蛋白降解相关的产品），其产品价格合理、质量可靠且具有创新性。目前VIVA Bioscience提供逾460种产品，涉及细胞自噬、蛋白泛素化和讲解相关的所有试剂盒、蛋白、底物以及多种抑制剂、激活剂等全系列产品。作为多家进口品牌的中国区域总代理，艾美捷科技与Viva Bioscience一道为中国科研工作者们提供更好、更新的自噬、泛素化和蛋白酶体等研究工具。

点击泛素蛋白 propargylamide (TAMRA)查看更详细产品说明，更多应用、储存、价格、货期等信息请致电垂询Viva Bioscience中国区域授权总代理艾美捷科技有限公司。