白介素-1受体相关激酶4抗体

白介素-1受体相关激酶4抗体产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

白介素-1受体相关激酶4抗体产品介绍

Interleukin 1 (IL1) and lipopolysaccharide (LPS) induces cellular responses through IL1 receptor (IL1R) and Toll like receptors (TLR). IL1R associated kinases (IRAK, IRAK2, and IRAKM) regulate the activation of NF-kB and MAP kinase (MAPK) by IL1R/TLR. A novel member in the IRAK/Pelle family was recently identified and designated IRAK4. Overexpression of IRAK4 activates NF-kB and MAPK pathways. IRAK4 interacts with and phosphorylates IRAK1. IRAK4 deficient animals are completely resistant to the challenge with LPS. Animals and humans lacking IRAK4 are impaired in their responses to viral and bacterial challenges. Members in IRAK/Pelle family play a central role in IL1R/TLR mediated inflammatory responses and in innate immunity.
mol wt:51kDa
Other Aliases:
8430405M07Rik, 9330209D03Rik, IPD1, IRAK4, NY-REN-64, REN64, INTERLEUKIN RECEPTOR-ASSOCIATED KINASE 4xy-0326R Rabbit Anti-Bov IgG兔抗牛IgG
xy-0310G Goat Anti-Chicken IgG羊抗鸡IgG
xy-0310R Rabbit Anti-chicken IgG兔抗鸡IgG
xy-0432M chicken IgY小鼠抗鸡IgY抗体
xy-0373R Dog IgM兔抗犬IgM抗体
xy-0296G Goat Anti-Mouse IgG羊抗小鼠IgG
xy-0294xy Donkey Anti-Goat IgG驴抗羊IgG
xy-0295G Goat Anti-rabbit IgG羊抗兔IgG
xy-0294R Rabbit Anti-Goat IgG兔抗羊IgG
xy-0294Rs Rabbit anti-Goat IgG whole serum兔抗羊IgG抗血清
xy-0358M Mouse Anti-Guinea pig IgG小鼠抗豚鼠IgG
xy-0308Rs Rabbit anti-horse IgG whole serum兔抗马IgG抗血清
xy-0297M Mouse Anti-human IgG小鼠抗人IgG
xy-0374R Rabbit Anti-horse IgM兔抗马IgM
xy-0297G Goat Anti-human IgG羊抗人IgG
xy-0297R Rabbit Anti-human IgG兔抗人IgG
xy-0360R Rabbit Anti-human IgA兔抗人免疫球蛋白A
xy-0377R Rabbit Anti-mouse IgG-Fc兔抗小鼠IgG-Fc
xy-0309R Rabbit Anti-pig IgG兔抗猪IgG
xy-0309Rs Rabbit anti-Pig IgG whole serum兔抗猪IgG抗血清
xy-0293Rs Rabbit anti-Rat IgG whole serum兔抗大鼠IgG抗血清
xy-0293M Mouse Anti-rat IgG小鼠抗大鼠IgG
xy-0293R Rabbit Anti-rat IgG兔抗大鼠IgG
xy-0295M Mouse Anti-rabbit IgG小鼠抗兔IgG
xy-0296R Rabbit Anti-mouse IgG兔抗小鼠IgG
xy-0335R Rabbit Anti-Monkey IgG兔抗猴IgG
xy-0346R Rabbit Anti-rat IgM兔抗大鼠IgM
xy-0369M Mouse Anti-Rabbit IgM小鼠抗兔IgM
xy-0346Rs Rabbit anti-Rat IgM whole serum兔抗大鼠IgM抗血清
xy-0295Gs Goat anti-Rabbit IgG whole serum羊抗兔IgG抗血清
白介素-1受体相关激酶4抗体