整合素α1抗体

整合素α1抗体产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

整合素α1抗体产品说明

Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces. They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit. Around twenty two different integrins (different alpha/ beta subunit combinations) are found in nature. Integrins are generally present in high concentrations at the cell surface, but, unlike most other cell surface receptors, they bind ligands with very low affinity. Due to their weak individual binding, integrins need to cluster and bind in groups in order to effectively bind the ECM. Integrins bind many different ligands including laminin. Each integrin is made up of a large N terminal extracellular domain that binds the ECM ligand and a small C terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton and signaling function. Alpha 1 integrin along with alpha 2, alpha L and alpha M has a unique inserted domain. Integrin alpha 1 is a receptor for laminin and collagen. The alpha1 subunit is also known as CD49a. CD49a associates with CD29 (beta 1 integrin), to form an alpha1 beta1 heterodimer, identified as the rat homologue to VLA1, which is involved in cellular adhesion to laminin and collagen.
mol wt:130kDa
Other Aliases:
Integrin alpha 1; CD49a; CD49a antigen; Itga 1; Itga1; Laminin and collagen receptor; Very late activation protein 1; VLA1

xy-11784R SPR墨蝶蛉还原酶抗体
xy-11787R alpha + beta Synuclein核突触蛋白α+β抗体
xy-11671R SPFH2内质网脂质转运相关蛋白2抗体
xy-11673R Serine racemase丝氨酸消旋酶
xy-11754R SCGN钙结合样蛋白/神经内分泌肿瘤标记物抗体
xy-11755R SFRS7丝氨酸/苏氨酸蛋白激酶SRPK7抗体
xy-11756R SGSH磺氨基葡糖硫酸胺酶抗体
xy-11757R SMUBP2免疫球蛋白μ链结合蛋白2抗体
xy-11785R SPG21痉挛性截瘫相关蛋白21抗体
xy-11759R SPG3AG蛋白结合蛋白3抗体
xy-11760R SPG48SPG48蛋白抗体
xy-11761R SPG7痉挛性截瘫蛋白7/基质细胞粘附调节蛋白抗体
xy-11762R SPTBN2非红细胞血影脑蛋白β2/spectrin β III抗体
xy-11763R SULT4A1脑磺基转移酶样蛋白4A1抗体
xy-11765R Synaptotagmin-14突触结合蛋白14抗体
xy-11766R TBPTATA结合蛋白TBP抗体
xy-11767R TBCE微管蛋白特定伴侣蛋白E抗体
xy-11768R TDRD3Tudor结构域蛋白TDRD3抗体
xy-11769R TIMM8A线粒体内膜转位酶8A/耳聋/肌张力障碍肽抗体
xy-11770R TMEM158跨膜蛋白158抗体
xy-11771R TTBK2Tau微管蛋白激酶2抗体
xy-11773R Transglutaminase 6谷氨酰胺转胺酶6抗体
xy-11648R TMEM59L跨膜蛋白59样蛋白抗体
xy-11775R Twinkle共济失调蛋白8抗体
xy-11603R TBR1TBR1蛋白抗体
xy-11605R TULP3感光细胞转录因子TULP3抗体
xy-11607R TsukushinTSK蛋白抗体
xy-11614R TAS2R5味觉受体蛋白家族2亚基5抗体
xy-11674R TPPP微管蛋白聚合促进蛋白24
xy-11068R Tenascin R腱糖蛋白R抗体
整合素α1抗体