The Small Animal Cystometry Lab Station is specifically designed for performing in vivo measurements of bladder function in mice and rats, and is ideal for physiological assessment of bladder performance in "Knock-Out" and transgenic mice.
This system allows standard urological tests to be performed in mice and rats. The experimental animal is chronically instrumented with an intra-bladder catheter, which is routed underneath the skin and exteriorized at the base of the animal's neck (this technique requires familiarity with small animal survival surgery). A computer-controlled syringe pump infuses saline into the bladder, and an in-line pressure transducer records intra-bladder pressure during the infusion. When bladder capacity is reached, the transducer records pressure during the urination event (micturition). An analytical balance, located beneath the animal cage, records the weight of urine, providing an index of voided urine volume. The entire system is enclosed in a Sound Attenuating Cubicle to isolate the animal from environmental disturbances. All signals are recorded on a PC-based system, which allows full user control of the cystometric protocol details.
Featuring ad lib access to food and water For users desiring to study bladder function (e.g. urine output) over a prolonged period of time, we have developed standard cystometry cages with food/water access for rats and mice that fit directly into our standard Small Animal Cystometry Lab Station.
Available in rat and mouse sizes (ENV-273A - Mouse; ENV-272A - Rat) Direct replacement for your existing rat or mouse cystometry cage.
Cystometry Analysis Software
New Data Analysis Software for Small Animal Cystometry Lab Station
Analyzing Cystometrograms Using Cystometry Analysis Software (SOF-552)
OS Compatibility: The Cystometry Data Analysis software may be installed on systems equipped
with Windows XP with Service Pack 2 or higher.
Automate the analysis of CMGs with Med Associates' Cystometry Analysis software (SOF-552). Cystometry Analysis works with the data acquired by your MED-CMG™ Small Animal Cystometry Lab Station.
Calculate Key Urodynamic Parameters
- Bladder Pressures
-
- Minimum
- Average
- Threshold
- Maximum
- Inter-micturition Interval
- Infused Volume
- Voided Volume
- Void Rate Index
- Also Measures Non-void Contractions
First, import the MED-CMG™ data into Cystometry Analysis. Cystometry Analysis displays up to four data traces in the main window in an easy-to-view "strip chart" fashion.
Several user-specified parameters can be set in order to optimize the analysis of micturition and non-void events.
Zoom in on the region of data to be analyzed, and place the analysis marks to define the micturition cycle start and end, the bladder pressure threshold, and the previous cycle's bladder threshold pressure.
Running the analysis routine finds the void event and any non-void contractions within the cycle of interest. Results are added to the spreadsheets at the bottom of the window. Results can be saved to a text file that can be opened and analyzed in any spreadsheet software, such as Excel.
Cystometry Analysis software also allows the user to print a report documenting the results. This feature is very useful for creating a hard copy record of each cystometry experiment.
CYSTOMETRY CAGES FOR RATS AND MICE
文献和实验
