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文献和实验Next-Generation HLA Sequencing Using the 454 GS FLX System
Next-generation sequencing (NGS) of HLA class I and II loci (HLA-A, HLA-B, HLA-C, DRB1, DRB3, DRB4, DRB5, DQA1, DQB1, DPB1) is described here in detail using the 454 Life Sciences GS FLX System and Titanium chemistry. An overview
Angiotensin type-1 receptors (AT1 receptors) mediate various physiological actions of angiotensin (Ang II) via multiple-signal transduction pathways (1 ). In addition to the phospholipase C pathway and dihydropyridine-sensitive voltage
with Roche Diagnostics and release of its GS20 sequencing machine in 2005 and GS FLX machine in 2007. As of 2005, the majority of 454's revenue came from sales of sequencing machines ($5.4 million), not in-house sequencing projects ($2.3 million).[2] 454
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