MCAD Polyclonal Antibody

Antigen: human recombinant MCAD • Host: rabbit • Cross Reactivity: (+) human, porcine, ovine, and mouse MCAD; other species not tested • Application(s): WB; other applications not tested • MCAD is a mitochondrial enzyme that catalyzes the first step in the β-oxidation of fatty acids. Its expression is induced during periods of fasting and is regulated by PPARα, a ligand-activated transcription factor involved in the regulation of lipid homeostasis. MCAD expression can be used as a marker to evaluate the in vivo activity of PPARα.