- ¥4480
- AssayPro
- 0.2 ng/ml
- 美国
- EMM5001-1
- 2026年01月14日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
大量
- 供应商：
AssayPro
- 检测范围：
0.2 ng/ml
- 检测方法：
ELISA
- 应用：
血清、血浆、细胞培养上清液
- 样本：
50 μl
- 规格：
96 wells
小鼠β2微球蛋白β2-MG酶联免疫试剂盒
β2-Microglobulin (β2M) is a small serum protein that constitutes thelight chain of the major histocompatibility class I human leukocyteantigen (HLA class I), an integral membrane protein involved in theimmune response. The protein is 99 amino acid residues in length and hasmolecular mass of 12 kDa (1 - 4). β2M is released from the cell surfaceof HLA class I into the serum and carried to the kidneys for degradationand secretion (5). In chronic renal failure, β2M accumulates asinsoluble amyloid aggregates and causes arthralgias, destructiveosteoarthropathies, carpal tunnel syndrome and dialysis-relatedamyloidosis (6 - 8). Elevated serum β2M levels are associated with poorprognosis in multiple myeloma and lymphoma (9 - 12).
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文献和实验检测血清β2 MG水平对判断手术预后和监测早期复发更具有重要意义。 【参考文献】 1、 蔡彦.β2微球蛋白在消化系统疾病诊治中的应用［J］.吉林医学，2004，25(8)：65-66. 2、Miyata T, Oda O, Inagi R, et al. Beta2Microglobulin modified with advanced glycation and products is a major component of hemodialysis
subsets, all noncovalently associated with 12 kd beta 2 microglobulin Function: restrict T cell responses to certain antigens; may mediate thymic T cell development Positive staining (normal): cortical thymocytes (70%), activated T cells
Genetic and Pharmacologic Models for Type 1 Diabetes
without autoimmune involvement, as do a variety of transgenes overexpressed in beta cells. Pharmacologically induced T1D (without autoimmunity) elicited by alloxan or streptozotocin at high doses can generate hyperglycemia in almost any strain of mouse by direct
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