- 询价
- TRC
- 进口原装
- TRC-T525500
- 2025年06月27日
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- 详细信息
- 文献和实验
- 技术资料
- 英文名：
Toceranib Discontinued Pfizer Patent issues
- 库存：
1
- 供应商：
甄准生物
- CAS号：
356068-94-5
- 规格：
5mg / 50mg
1) Cat. No.: TRC-T525500; 2) Chemical Name: Toceranib Discontinued Pfizer Patent issues; 3) CAS No.: 356068-94-5; 4) Mol. Formula: C22H25FN4O2; 5) Mol. Weight: 396.46; 6) Packing Size: 5mg / 50mg; 7) Appearence: ; 8) Application Notes: Toceranib is a multitargeted indolinone receptor tyrosine kinase (RTK) inhibitor. Toceranib exhibited activity against a variety of spontaneous malignancies in canine such as mast cell tumors, mixed mammary carcinomas, soft tissue sarcomas, and multiple myeloma.; 9) Synonym: 5-[(Z)-(5-Fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-N-[2-(1-pyrrolidinyl)ethyl]-1H-pyrrole-3-carboxamide; 5-(5-Fluoro-2-oxo-1,2-dihydroindol-(3Z)-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid (2-(Pyrrolidin-1-yl)ethyl)amide; PHA 291639; SU 11654;; 10) Solubility: ; 11) Storage condition: ; 12) References: London, C.A. et al.: Clin. Cancer Res., 9, 2755 (2003); Zavodovskaya, R. et al.: Am. J. vVt. Res., 67, 633 (2006); Malone, E.K. et al.: Vet. Comp. Oncol., 8, 209 (2010);
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文献和实验相关实验
【翻译】Development trends for monoclonal antibody cancer therapeutics
; they are more difficult to manufacture and may have greater safety issues compared with their naked counterparts. Despite this, immunoconjugates of various kinds constituted 44% of the total anticancer mAbs in clinical study to date (Fig. 2). Figure 2 | Modes of action
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Toceranib
Discontinued Pfizer Patent issues
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