CHIR-99021

1) Cat. No.: TRC-C292150; 2) Chemical Name: CHIR-99021; 3) CAS No.: 252917-06-9; 4) Mol. Formula: C22H18Cl2N8; 5) Mol. Weight: 465.34; 6) Packing Size: 10mg / 100mg; 7) Appearence: ; 8) Application Notes: CHIR-99021 is a potent and highly selective inhibitor of glycogen synthase kinase 3 (GSK-3). CHIR-99021 activates glycogen synthesis in CHO-IR cells and in isolated type 1 diabetic rat skeletal muscle. CHIR-99021 has also been shown to induce the reprogramming of murine and human somatic cells into stem cells.; 9) Synonym: 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile; CHIR 911; CT 99021; ; 10) Solubility: ; 11) Storage condition: ; 12) References: Ring, et al.: Diabetes, 52, 588 (2003); Tighe, et al.: Cell Biol., 8, 34 (2007); Pan, et al.: Neuropsychopharmacology, 36, 1397 (2011);