CD10 Antibody 抗体,orb2644618,Biorbyt产品图

CD10 Antibody 抗体,orb2644618,Bi

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  • ¥8775
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  • orb2644618
  • 英国
  • 2026年08月07日
  • IHC-P
  • Mouse
  • Human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 抗体名:

      CD10 Antibody 抗体

    • 抗体英文名:

      CD10 Antibody

    • 应用范围:

      IHC-P

    • 宿主:

      Mouse

    • 适应物种:

      Human

    • 保质期:

      12 months from date of receipt.

    • 抗原来源:

      详询

    • 目录编号:

      orb2644618

    • 级别:

      科研

    • 库存:

      99

    • 供应商:

      Biorbyt

    • 标记物:

      Unconjugated

    • 克隆性:

      Monoclonal

    • 保存条件:

      详询

    • 亚型:

      Mouse IgG2b, kappa

    • 免疫原:

      详询

    • 规格:

      100 ug

    类别: Antibodies

    产品子类型: Primary Antibody

    描述: Recognizes a 100kDa glycoprotein, identified as CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt s, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.

    克隆号: MME/3739

    应用稀释比例: Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT

    应用说明: Optimal dilution of the CD10 antibody should be determined by the researcher.

    免疫原: A portion of amino acids 297-483 from the human protein was used as the immunogen for the CD10 antibody.

    防腐剂: 1 mg/ml in 1X PBS; rAlbumin free, sodium azide free

    纯化方法: Protein G affinity chromatography

    研究领域: Neuroscience; Immunology & Inflammation

    UniProt ID: P08473

    保存条件: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

    备注: For research use only.

    产品细节图片1
    IHC staining of FFPE human kidney with CD10 antibody (clone MME/3739). HIER: boil tissue sections in pH9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

    产品细节图片2
    IHC staining of FFPE human kidney with CD10 antibody (clone MME/3739). HIER: boil tissue sections in pH9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

    产品细节图片3
    Analysis of HuProt (TM) microarray containing more than 19000 full-length human proteins using CD10 antibody. These results demonstrate the foremost specificity of the MME/3739 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt (TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt (TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.

    产品细节图片4
    SDS-PAGE analysis of purified, BSA-free CD10 antibody (clone MME/3739) as confirmation of integrity and purity.

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    图标文献和实验
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      of patients with open heart surgery the expression of the membrane peptidases neprilysin/CD10 and aminopeptidase N/CD13, was determined on granulocytes in comparison to the monocytic HLA-DR expression. We used the QuantiBRITE™ flow cytometry

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    • 淋巴细胞群及其亚群

      cell) 成熟B细胞被相应抗原或多克隆刺激剂刺激后成为活化B细胞,断而发生增殖和分化,在此过程中,膜结合Ig水平逐渐降低,而分泌型Ig逐渐增加,并可发生免疫球蛋白基因重链类别的转换。活化B细胞中的一部分可分化为小淋巴细胞,停止增殖和分化,并可存活数月至数年,当再次与同一抗原接触时,很快发生活化和分化,产生抗体的潜伏期短,抗体水平高,维持时间长,这种B细胞称为记忆B细胞(memory B cell)。   5.浆细胞(plasma cell,PC) 又称抗体分泌细胞(antibody

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