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- 文献和实验
- 技术资料
- 保存条件:
2-8度
- 保质期:
1年
- 英文名:
Ulinastatin
- 库存:
999
- 供应商:
上海淳麦生物
- 规格:
/5ug/20ug/1mg
产品英文名称:
Recombinant Human Urinary Trypsin Inhibitor (UTI)
英文简称:
Ulinastatin
中文名称:
重组人尿胰蛋白酶抑制剂(UTI)
背景资料:
Urinary-Trypsin Inhibitor is a glucoprotein proteinase inhibitor with a molecular weight of about 67,000 derived from human urine which inhibits the activity of trypsin, chymotrypsin, lactate, lipase, hyaluronidase and various pancreatic enzymes. Ulinastatin is e毕赤酵母中重组表达ective for acute pancreatitis, chronic recurrent pancreatitis and hemorrhagic, traumatic and endotoxic shocks. Ulinastatin is has strong inhibition e毕赤酵母中重组表达ect to various protease, sugar and fat hydrolase. Ulinastatin precursor is proteolytically processed into distinct functioning proteins. urinary trypsin inhibitor belongs to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. Uristatin gene is located on chromosome 9 in a cluster of lipocalin genes. High levels of Ulinastatin secretion is an early marker of renal tubular involvement and has radical scavenging activity. Bikunin localizes cell membrane. FrRecombinant Ulinastatin produced in Yeast is a single, glycosylated, polypeptide having 143 amino acids, molecular mass of 20 kDa and predicted pI of 4.5. uristatin and bikunin pass readily into urine and are primarily bound to heavy chains that constitute the proinhibitor form in plasma. Ulinastatin particularly interacts with ORF3 protein of hepatitis E virus and in charge for enhancing alpha microglobulin export from the hepatocyte.
产品描述:
Recombinant Ulinastatin produced in Yeast is a single, glycosylated, polypeptide having 143 amino acids, molecular mass of 20 kDa and predicted pI of 4.5.
来源宿主:
毕赤酵母中重组表达
溶解建议:
Sterile Filtered solution. Formulated in 1X PBS.
保存建议:
Ulinastatin although stable at 15℃ for 2 weeks, should be stored desiccated below -18℃. Please prevent freeze-thaw cycles.
应用领域:
重组人尿胰蛋白酶抑制剂(UTI)产品可广泛应用于酶活性研究、代谢研究、功能研究、蛋白互作研究、ELISA检测、Western Blot、免疫组化等生物医学研究领域。
关键词:
重组人尿胰蛋白酶抑制剂(UTI)、Recombinant Human Urinary Trypsin Inhibitor (UTI)、Ulinastatin、重组蛋白、多肽、酶类、酵母表达、CMBIO
其他简介:
CMBIO
Recombinant Human Urinary Trypsin Inhibitor (UTI)
英文简称:
Ulinastatin
中文名称:
重组人尿胰蛋白酶抑制剂(UTI)
背景资料:
Urinary-Trypsin Inhibitor is a glucoprotein proteinase inhibitor with a molecular weight of about 67,000 derived from human urine which inhibits the activity of trypsin, chymotrypsin, lactate, lipase, hyaluronidase and various pancreatic enzymes. Ulinastatin is e毕赤酵母中重组表达ective for acute pancreatitis, chronic recurrent pancreatitis and hemorrhagic, traumatic and endotoxic shocks. Ulinastatin is has strong inhibition e毕赤酵母中重组表达ect to various protease, sugar and fat hydrolase. Ulinastatin precursor is proteolytically processed into distinct functioning proteins. urinary trypsin inhibitor belongs to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. Uristatin gene is located on chromosome 9 in a cluster of lipocalin genes. High levels of Ulinastatin secretion is an early marker of renal tubular involvement and has radical scavenging activity. Bikunin localizes cell membrane. FrRecombinant Ulinastatin produced in Yeast is a single, glycosylated, polypeptide having 143 amino acids, molecular mass of 20 kDa and predicted pI of 4.5. uristatin and bikunin pass readily into urine and are primarily bound to heavy chains that constitute the proinhibitor form in plasma. Ulinastatin particularly interacts with ORF3 protein of hepatitis E virus and in charge for enhancing alpha microglobulin export from the hepatocyte.
产品描述:
Recombinant Ulinastatin produced in Yeast is a single, glycosylated, polypeptide having 143 amino acids, molecular mass of 20 kDa and predicted pI of 4.5.
来源宿主:
毕赤酵母中重组表达
溶解建议:
Sterile Filtered solution. Formulated in 1X PBS.
保存建议:
Ulinastatin although stable at 15℃ for 2 weeks, should be stored desiccated below -18℃. Please prevent freeze-thaw cycles.
应用领域:
重组人尿胰蛋白酶抑制剂(UTI)产品可广泛应用于酶活性研究、代谢研究、功能研究、蛋白互作研究、ELISA检测、Western Blot、免疫组化等生物医学研究领域。
关键词:
重组人尿胰蛋白酶抑制剂(UTI)、Recombinant Human Urinary Trypsin Inhibitor (UTI)、Ulinastatin、重组蛋白、多肽、酶类、酵母表达、CMBIO
其他简介:
CMBIO




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文献和实验该产品被引用文献
Si-Tong Li et al. Ulinastatin attenuates LPS-induced inflammation in mouse macrophage RAW264.7 cel... Acta Pharmacol Sin 2018. PMID:29323338
Chunze Zhang et al. A Meta-analysis on the Effect of Ulinastatin on Serum Levels of C-Reactive Prote... Genet Test Mol Biomarkers 2016. PMID:26780230
相关实验
响。 f:流速:在压力许可下,无明显影响。 g、样品浓度:在粘度不超过5cP下,无影响。 h、梯度:较缓的梯度分辨较好。 四、一些蛋白质的分子量与Stokes半径: 蛋白质 分子量(kD) Stokes半径(nm) 乳清蛋白 12.4 2.01 核糖核酸酶 13.7 1.92 肌红蛋白 17.0 2.00 大豆胰蛋白酶抑制剂 21.5 2.26 碳酸酐酶 31.0 2.35 辣根过氧化物歧化酶 40 3.00 卵清蛋白 45 2.80 血红
用于治疗各种纤溶亢进所致的出血,如肺、肝、胰、前列腺、甲状腺、肾上腺等手术所致的出血,产后出血、前列腺肥大出血、上消化道出血等,因为这些脏器及尿内存有较大量纤溶酶原激活因子。但对癌症出血、创伤出血及非纤维蛋白溶解引起的出血无止血效果。 PAMBA不良反应少,但应用过量可致血栓,并可能诱发心肌梗死。 氨甲环酸 Tranexamic acid Tranexamin acid (AMCHA)又称凝血酸。其止血原理与PAMBA相同,但作用较强。用于预防和治
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文献支持
重组人尿胰蛋白酶抑制剂(UTI)(Ulinastatin)
¥700 - 1500








