更昔洛韦(GCV)

产品英文名称：
Ganciclovir

英文简称:
GCV

中文名称:
更昔洛韦

背景资料:
Ganciclovir （GCV） is a pro-drug nucleoside analog that is activated by phosphorylation. It is useful in the study of gene therapy in cancer research. Ganciclovir is a synthetic analogue of 2’-deoxy-guanosine. It is initially phosphorylated to a deoxyguanosine triphosphate （dGTP） analogue. This mechanism competitively inhibits the integration of dGTP by viral DNA polymerase， resulting in the termination of elongation of viral DNA. Upon expression of a viral suicide gene encoding thymidine kinase， the non-toxic pro-drug is converted to a phosphorylated active analog and is incorporated into the DNA of replicating eukaryotic cells， causing death of the malignant dividing cell. The cell cycle is irreversibly arrested at the G2-M checkpoint. Gap junction involvement in the ganciclovir bystander eect has bGanciclovir is a white to o-white crystalline powder with a molecular formula of C9H13N504 and a molecular weight of 255.23.n studied. Ganciclovir has bGanciclovir is a white to o-white crystalline powder with a molecular formula of C9H13N504 and a molecular weight of 255.23.n used to study loss of telomeres and to evaluate sensitivity of viruses to antiviral treatments. Ganciclovir is used in molecular biology for selection against random recombination events when homologous recombination of a gene of interest is required.

产品描述:
Ganciclovir is a white to o-white crystalline powder with a molecular formula of C9H13N504 and a molecular weight of 255.23.
来源宿主:

溶解建议:
Sterile Filtered White lyophilized （freeze-dried） powder. It is recommended to reconstitute the lyophilized Ganciclovir in sterile 18MΩ-cm H2O not less than 100ug/ml， which can then be further diluted to other aqueous solutions.

保存建议：
Lyophilized Ganciclovir although stable at room temperature for 3 weeks， should be stored at 4℃.
应用领域：
更昔洛韦产品可广泛应用于免疫检测研究、抗体开发、ELISA检测、Western Blot、免疫组化等生物医学研究领域。

关键词：
更昔洛韦、Ganciclovir、GCV、蛋白质/抗原/多肽、CMBIO、淳麦生物、科研试剂、生物试剂

其他简介：

 
CMBIO