DR5 Antibody / TRAIL R2 / TNFRSF10B / CD262 抗体,orb640015,Biorbyt产品图

DR5 Antibody / TRAIL R2 / TNFR

SF10B / CD262 抗体,orb640015,Biorbyt
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  • ¥4329 - 8775
  • Biorbyt已认证
  • orb640015
  • 英国
  • 2026年07月29日
  • IHC-P
  • Mouse
  • Human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 抗体名

      DR5 Antibody / TRAIL R2 / TNFRSF10B / CD262 抗体

    • 抗体英文名

      DR5 Antibody / TRAIL R2 / TNFRSF10B / CD262

    • 应用范围

      IHC-P

    • 宿主

      Mouse

    • 适应物种

      Human

    • 保质期

      12 months from date of receipt.

    • 抗原来源

      详询

    • 目录编号

      orb640015

    • 级别

      科研

    • 库存

      99

    • 供应商

      Biorbyt

    • 标记物

      Unconjugated

    • 克隆性

      Monoclonal

    • 保存条件

      详询

    • 亚型

      Mouse IgG1, kappa

    • 免疫原

      详询

    • 规格

      20 ug/100 ug

    规格:20 ug产品价格:¥4329.0
    规格:100 ug产品价格:¥8775.0
    类别: Antibodies

    产品子类型: Primary Antibody

    描述: Tumor necrosis factor (TNF) is a pleiotropic cytokine whose function is mediated by two distinct cell surface receptors, designated TNF-R1 and TNF-R2, which are expressed on most cell types. TNF function is primarily mediated through TNF-R1 signaling. Both receptors belong to the growing TNF receptor superfamily which includes Fas antigen and CD40. TNF-R1 contains a cytoplasmic motif, termed the death domain, that has been found to be necessary for the transduction of the apoptotic signal. The death domain is also found in several other receptors, including Fas, DR2 (or TRUNDD), DR3 (death receptor 3), DR4 and DR5. TRUNDD, DR4 and DR5 are receptors for the apoptosis-inducing cytokine TRAIL. A non-death domain-containing receptor, designated decoy receptor (DcR1 or TRID), also specifically associates with TRAIL and may play a role in cellular resistance to apoptotic stimuli.

    克隆号: DR5/3381

    应用稀释比例: Immunohistochemistry (FFPE): 1-2ug/ml

    应用说明: Optimal dilution of the DR5 antibody should be determined by the researcher.

    免疫原: A recombinant protein partial protein (amino acids 266-393) was used as the immunogen for this DR5 antibody.

    防腐剂: 0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide

    纯化方法: Protein G affinity chromatography

    研究领域: Immunology & Inflammation; Cell Biology

    UniProt ID: O14763

    保存条件: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

    备注: For research use only.

    产品细节图片1
    IHC staining of FFPE human breast carcinoma with DR5 antibody. HIER: boil tissue sections in pH9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

    产品细节图片2
    IHC staining of FFPE human colon carcinoma with DR5 antibody. HIER: boil tissue sections in pH9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

    产品细节图片3
    Analysis of HuProt (TM) microarray containing more than 19000 full-length human proteins using DR5 antibody (clone DR5/3381). These results demonstrate the foremost specificity of the DR5/3381 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt (TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt (TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.

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    图标文献和实验
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    • Dynabeads® CD3CD28 CTS

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    • T-Cell Activation Using mAb to CD3

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    ¥4329 - 8775