Recombinant TL1A Antibody / TNFSF15 / VEGI 抗体,orb606460,Biorbyt产品图

Recombinant TL1A Antibody / TN

FSF15 / VEGI 抗体,orb606460,Biorbyt
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  • ¥4329 - 8775
  • Biorbyt已认证
  • orb606460
  • 英国
  • 2026年07月29日
  • IHC-P
  • Mouse
  • Human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 抗体名:

      Recombinant TL1A Antibody / TNFSF15 / VEGI 抗体

    • 抗体英文名:

      Recombinant TL1A Antibody / TNFSF15 / VEGI

    • 应用范围:

      IHC-P

    • 宿主:

      Mouse

    • 适应物种:

      Human

    • 保质期:

      12 months from date of receipt.

    • 抗原来源:

      详询

    • 目录编号:

      orb606460

    • 级别:

      科研

    • 库存:

      99

    • 供应商:

      Biorbyt

    • 标记物:

      Unconjugated

    • 克隆性:

      Recombinant

    • 保存条件:

      详询

    • 亚型:

      Mouse IgG1, kappa

    • 免疫原:

      详询

    • 规格:

      20 ug/100 ug

    规格:20 ug产品价格:¥4329.0
    规格:100 ug产品价格:¥8775.0
    类别: Antibodies

    产品子类型: Primary Antibody

    描述: TNF ligand-related molecule 1 is an anti-angiogenic cytokine that is also called Tumor necrosis factor superfamily, member 15 (TNFSF15) and Vascular endothelial growth inhibitor (VEGI/VEGI192A). This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Reduced expression of TL1A/TNFSF15/VEGI has been reported as a marker of poor prognosis in breast cancer.

    克隆号: rVEGI/1283

    应用稀释比例: Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT

    应用说明: Titration of the recombinant TL1A antibody may be required for optimal performance.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

    免疫原: A full length human recombinant protein was used as the immunogen for this recombinant TL1A antibody.

    防腐剂: 0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide

    纯化方法: Protein G affinity chromatography

    研究领域: Epigenetics

    UniProt ID: O95150

    保存条件: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

    备注: For research use only.

    产品细节图片1
    Analysis of HuProt (TM) microarray containing more than 19, 000 full-length human proteins using recombinant TL1A antibody (clone rVEGI/1283). These results demonstrate the foremost specificity of the rVEGI/1283 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt (TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt (TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.

    产品细节图片2
    IHC testing of FFPE human spleen with recombinant TL1A antibody (clone rVEGI/1283). Required HIER: boil sections in 10mM Tris with 1mM EDTA, pH9, for 10-20 min followed by cooling at RT for 20 min.

    产品细节图片3
    SDS-PAGE analysis of purified, BSA-free recombinant TL1A antibody (clone rVEGI/1283) as confirmation of integrity and purity.

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