- ￥7700
- DIMA BIOTECH/缔码生物
- 武汉
- FLP400014B
- 2026年07月09日
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- 文献和实验
- 技术资料
- 保存条件：
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 保质期：
12个月
- 英文名：
Biotinylated Human CLDN18.2 full length protein-PeptiNanodisc
- 库存：
In Stock
- 供应商：
缔码生物（武汉）科技有限公司
- 规格：
10μg
| 产品类型 | Full Length Transmembrane Proteins |
|---|---|
| 靶点 | CLDN18.2 |
| Uniprot ID | P56856-2 |
| 背景 | A member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| 货期 | In Stock |
| 产品英文名称 | Biotinylated Human CLDN18.2 full length protein-PeptiNanodisc |
| 分子量 | The human full length CLDN18.2 Protein has a MW of 27.5 kDa |
| 蛋白家族 | Transmembrane |
| 信号通路 | Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction |
| 无菌性 | Products are supplied non-sterile. For cell culture applications, dilute in appropriate medium and sterile-filter (0.22 µm) prior to use. |
| 储存与运输 | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| 别名 | SFTA5; SFTPJ |
| 标签 | C-Flag&Avi Tag |
| 有无偶联 | Biotinylated |
| 表达宿主 | HEK293 |
| 组分 | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| 应用范围 | Research use only |
Figure 1. Elisa plates were added with C-Flag&Avi Tag Biotinylated CLDN18.2-PeptiNanodisc (0.2μg/per well) on a Streptavidin pre-coated (0.2μg/per well) plate. Serial diluted anti-CLDN18.2 monoclonal antibody (DME100179) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-CLDN18.2 monoclonal antibody binding with Biotinylated CLDN18.2-PeptiNanodisc is 5.94ng/ml.
Figure 2. Biotinylated Human CLDN18.2-PeptiNanodisc, C-Flag&Avi Tag on SDS-PAGE
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