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- 文献和实验
- 技术资料
- CAS号:
432531-71-0
- 规格:
1mLx10mM(inDMSO)/1mg/2mg/5mg/10mg/25mg/50mg/100mg/500mg
| 规格: | 1mLx10mM(inDMSO) | 产品价格: | ¥369.0 |
|---|---|---|---|
| 规格: | 1mg | 产品价格: | ¥150.0 |
| 规格: | 2mg | 产品价格: | ¥218.0 |
| 规格: | 5mg | 产品价格: | ¥333.0 |
| 规格: | 10mg | 产品价格: | ¥478.0 |
| 规格: | 25mg | 产品价格: | ¥928.0 |
| 规格: | 50mg | 产品价格: | ¥1456.0 |
| 规格: | 100mg | 产品价格: | ¥2384.0 |
| 规格: | 500mg | 产品价格: | ¥5504.0 |
Product Introduction
Bioactivity
| 名称 | (E/Z)-Necrosulfonamide |
| 描述 | (E/Z)-Necrosulfonamide is a novel inhibitor of MLKL. |
| 动物实验 | Pathologic condition was detected using hematoxylin-eosin staining on injured spinal cord and other major organs. Necroptosis-related factors-RIP1, RIP3, and MLKL-were detected using Western blot. Detections on mitochondrial functions such as adenosine triphosphate generation and activities of superoxide dismutase and caspase-3 were also performed. Finally, ethologic performance was detected using a 21-point open-field locomotion test[1]. |
| 体内活性 | Necrosulfonamide attenuates the spinal cord injury via necroptosis inhibition[1] |
| 存储条件 | Store at low temperature,Keep away from direct sunlight,Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | DMSO : 25 mg/mL (54.17 mM), Sonication is recommended. |
| 关键字 | Necrosulfonamide | necrosis(MLKL) |
| 相关产品 | Allopurinol | Kaolin | Magnesium acetate tetrahydrate | Dimethyl phthalate | Aceglutamide | Stavudine | Imeglimin hydrochloride | Gluconate Calcium | Ethoxyquin | D(+)-Raffinose pentahydrate | Ethyl linoleate | Hydroxypropyl Cellulose |
| 相关库 | Inhibitor Library | Bioactive Compound Library | Bioactive Compounds Library Max | Transcription Factor-Targeted Compound Library | Kinase Inhibitor Library | NO PAINS Compound Library | Anti-Ovarian Cancer Compound Library | Anti-Obesity Compound Library | Immunology/Inflammation Compound Library | Pain-Related Compound Library | Ferroptosis Compound Library | Reprogramming Compound Library |
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文献和实验E-Z 96 X-press Plasmid Vacuum Protocol
well plate inside the manifold base; 3) Place the top plate of manifold over the base, the deep well plate or waste collection tray now should be positioned under the E-Z 96 X-press Plate. Seal the unused wells of E-Z 96 Xpress Plate with sealing
E-Z 96 X-press Plasmid Spin Protocol
-well plate. Transfer the cell lysate to each well of E-Z 96 X-press plate. 3. Centrifuge at 3000 x g for 5 minutes at room temperature. Discard the flow-through and re-use the deep well plate. 4. Add 500μl DLW Buffer (diluted with isopropanol
E. Z. N.A.TM X-press Plasmid Protocol
实验试剂 Materials to Be Provided by User 1. Ice 2. Isopropanol (100%) 实验设备 Materials to Be Provided by User 1. Tabletop micro-centrifuge capable of 13,000 x g 2. Nuclease Free
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