化合物 (E/Z)-Necrosulfonamide【432531-71-0】产品图
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化合物 (E/Z)-Necrosulfonamide【432

531-71-0】
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  • ¥150 - 5504
  • TargetMol
  • T7129
  • 2026年07月07日
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    • 文献和实验
    • 技术资料
    • CAS号

      432531-71-0

    • 规格

      1mLx10mM(inDMSO)/1mg/2mg/5mg/10mg/25mg/50mg/100mg/500mg

    规格:1mLx10mM(inDMSO)产品价格:¥369.0
    规格:1mg产品价格:¥150.0
    规格:2mg产品价格:¥218.0
    规格:5mg产品价格:¥333.0
    规格:10mg产品价格:¥478.0
    规格:25mg产品价格:¥928.0
    规格:50mg产品价格:¥1456.0
    规格:100mg产品价格:¥2384.0
    规格:500mg产品价格:¥5504.0

    Product Introduction

    Bioactivity

    名称 (E/Z)-Necrosulfonamide
    描述 (E/Z)-Necrosulfonamide is a novel inhibitor of MLKL.
    动物实验 Pathologic condition was detected using hematoxylin-eosin staining on injured spinal cord and other major organs. Necroptosis-related factors-RIP1, RIP3, and MLKL-were detected using Western blot. Detections on mitochondrial functions such as adenosine triphosphate generation and activities of superoxide dismutase and caspase-3 were also performed. Finally, ethologic performance was detected using a 21-point open-field locomotion test[1].
    体内活性 Necrosulfonamide attenuates the spinal cord injury via necroptosis inhibition[1]
    存储条件 Store at low temperature,Keep away from direct sunlight,Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
    溶解度 DMSO : 25 mg/mL (54.17 mM), Sonication is recommended.
    关键字 Necrosulfonamide | necrosis(MLKL)
    相关产品 Allopurinol | Kaolin | Magnesium acetate tetrahydrate | Dimethyl phthalate | Aceglutamide | Stavudine | Imeglimin hydrochloride | Gluconate Calcium | Ethoxyquin | D(+)-Raffinose pentahydrate | Ethyl linoleate | Hydroxypropyl Cellulose
    相关库 Inhibitor Library | Bioactive Compound Library | Bioactive Compounds Library Max | Transcription Factor-Targeted Compound Library | Kinase Inhibitor Library | NO PAINS Compound Library | Anti-Ovarian Cancer Compound Library | Anti-Obesity Compound Library | Immunology/Inflammation Compound Library | Pain-Related Compound Library | Ferroptosis Compound Library | Reprogramming Compound Library

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    图标文献和实验
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    相关实验
    • E-Z 96 X-press Plasmid Vacuum Protocol

      well plate inside the manifold base;    3) Place the top plate of manifold over the base, the deep well plate or waste collection tray now should be positioned under the E-Z 96 X-press Plate. Seal the unused wells of E-Z 96 Xpress Plate with sealing

    • E-Z 96 X-press Plasmid Spin Protocol

      -well plate. Transfer the cell lysate to each well of E-Z 96 X-press plate. 3. Centrifuge at 3000 x g for 5 minutes at room temperature. Discard the flow-through and re-use the deep well plate. 4. Add 500μl DLW Buffer (diluted with isopropanol

    • E. Z. N.A.TM X-press Plasmid Protocol

      实验试剂   Materials to Be Provided by User 1. Ice 2. Isopropanol (100%) 实验设备   Materials to Be Provided by User 1. Tabletop micro-centrifuge capable of 13,000 x g 2. Nuclease Free

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    文献支持
    化合物 (E/Z)-Necrosulfonamide【432531-71-0】
    ¥150 - 5504