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- 详细信息
- 文献和实验
- 技术资料
- CAS号：
152-11-4
- 规格：
1g/1mLx10mM(inDMSO)/500mg
| 规格： | 1g | 产品价格： | ￥347.0 |
|---|---|---|---|
| 规格： | 1mLx10mM(inDMSO) | 产品价格： | ￥306.0 |
| 规格： | 500mg | 产品价格： | ￥287.0 |
Product Introduction
Bioactivity
| 名称 | Verapamil hydrochloride |
| 描述 | Verapamil hydrochloride (Verapamil HCl) is a calcium channel blocker that is a class IV anti-arrhythmia agent. |
| 细胞实验 | Verapamil is dissolved in DMSO and stored, and then diluted with appropriate media before use[1]. Cells (1×105) are treated with 10 nM Bortezomib and/or 70 μM Verapamil for 16 hours and incubated for another 4 hours with Alamar-Blue. Activity of the mitochondrial dehydrogenase results in conversion of the coloring, which is followed by measurement of the absorption using a spectrophotometer[1]. |
| 体外活性 | Verapamil可以抗心律失常,减少大鼠心脏氧的消耗,并保存Cx43蛋白. |
| 体内活性 | Verapamil和Diltiazem能够基本上抑制重组CES2的水解酶活性(Ki分别为0.25 ± 0.02、3.84 ± 0.99 μM)。 |
| 存储条件 | Keep away from direct sunlight,Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (4.07 mM), Sonication is recommended. DMSO : 86.67 mg/mL (176.5 mM), Sonication is recommended. H2O : 24.6 mg/mL (50.1 mM), Sonication is recommended. |
| 关键字 | Verapamil hydrochloride | Verapamil hydrochlorid | Verapamil | pressure | P-gp (P-glycoprotein) | P-gp | Pgp | P-glycoprotein | Palbociclib | Multidrug resistance protein 1 | MDR1 | lysosomotropic | Inhibitor | inhibit | high | Cytochrome P450 | CYPs | CYP3A4 | Cluster of differentiation 243 | CD243 | CalciumChannel | Calcium Channel | Calcan Hydrochloride | Ca2+ channels | Ca channels | blood | antiarrhythmic | angina | ABCB1 | (±)-Verapamil |
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| 相关库 | Neuroprotective Compound Library | Inhibitor Library | Bioactive Compound Library | Anti-Cancer Approved Drug Library | Bioactive Compounds Library Max | Anti-Aging Compound Library | FDA-Approved Drug Library | Membrane Protein-targeted Compound Library | Anti-Neurodegenerative Disease Compound Library | Pain-Related Compound Library | Drug Repurposing Compound Library | Anti-Cancer Clinical Compound Library |
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文献和实验统计学意义 例20.6根据以往经验，一般溃疡病患者中有20%发生胃出血症状。某医生观察65岁以上溃疡病人152例，其中48例发生胃出血症状，问老年患者出血情况与一般患者有无不同？ 按惯例大量观察所得的率可当作总体率看待，则本例总体率π为0.2(20%)，1-π=0.8，n=152 标准误差 样本率 p=48/152×100%=31.6%=0.316 检验步骤： 1．建立检验
【共享】推荐免疫诊断的教材：Clinical Immunology And Serology - A Laboratory Perspective （免叮当）
8: Precipitation Reactions 123Chapter 9: Agglutination 137Chapter 10: Labeled Immunoassays 152Chapter 11: Molecular Diagnostic Techniques 166Chapter 12: Flow Cytometry and Laboratory Automation 186Section 3: Immune Disorders 201Chapter 13: Hypersensitivity 202
CANDOR BIOSCIENCE: 关于ELISA板稳定性的技术探讨与比较
2 Remarkable immunogenicity and protective efficacy of BBV152, an inactivated SARS-CoV-2 vaccine in rhesus macaques 3 Accurate determination of soluble Axl by enzyme-linked immunosorbent assay 4 Rapidly produced SAM® vaccine
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